Compare airlines, prices, and flight durations for your trip
Cheapest flights from Quito to Panama City
Fly from Quito to Panama City with confidence — we search over 700 airlines, 50+ agencies and 5+ top booking systems to uncover the best prices, schedules and ticket conditions for your trip. Friendly comparisons and real-time options make it easy to pick the flight that fits your budget and timing so you can focus on exploring Panama City.
Remember that on average the ideal time to book flights is 2 months before departure!
In different months, ticket prices from Quito to Panama City vary: minimum — $242 (January 2026), maximum — $247 (February 2026). Typically, the flight costs $244–$491.
Airlines operating on route
Non-stop flights from Quito to Panama City
Fly direct from Quito to Panama City for the quickest, most convenient way to connect Ecuador’s highland charm with Panama’s vibrant waterfront. While you may occasionally find cheaper connecting options, a nonstop flight saves hours and reduces hassle so you arrive rested and ready to explore. Book now to enjoy the comfort and time-savings of a direct trip between these two dynamic cities.
Schedule of direct flights from Quito to Panama City
A direct flight is the easiest way to get to your destination. The following airlines operate non-stop flights from Quito to Panama City:
Quito airports overview
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Panama City airports overview
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Frequently asked questions (FAQ)
Answers to questions about the route that travelers are most interested in.
Special offers and sales on air tickets from Quito to Panama City
We keep tight track on airlines' pre-holidays sales and other special offers occurences all the time to let you save maximum amount of funds while traveling to your family or just going out on vacation.
Alternative routes
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Cheapest one way flight
$222
Avianca
2 layovers
7h 30m
02/07/2026
The cheapest one-way flight from Quito to Panama City departs on 02/07/2026, is operated by Avianca and costs $222
Cheapest round trip flight
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There is no information about the cheapest roundtrip flight from Quito to Panama City
The fastest flight
7h 30m
Fastest flight from Quito to Panama City takes 7h 30m
Direct flights
Several times a week
There are direct flights on this route 5 days a week: Su, Tu, We, Fr, and Sa
Earliest flight
6:00 AM
Latest flight
3:11 AM
Direct flights count
39
Distance
1022km
Timezone difference
0h
The distance between Quito and Panama City is 1022km (634 miles). There are 39 direct flights from Quito to Panama City. Quito and Panama City are in the same time zone. Flights from Quito begin at 6:00 AM. The latest flight from Quito departs at 3:11 AM
January 2026
Lowest price
on average:
$242
February 2026
Highest price
on average:
$247
Avg Price
The Quito — Panama City route is served by multiple airlines, including Copa Airlines and Avianca. This is convenient for those who want the best balance of price, schedule, and travel conditions. Tickets start from $222, and depending on season and promotions, even better deals may appear. With our service, you can easily compare available options and book tickets that match your plans. The variety of carriers allows flexible choices and comfortable travel without overpaying.
Mariscal Sucre International Airport (UIO) is Quito’s primary international gateway, serving a mix of full-service and regional carriers and acting as the country’s main long-haul hub rather than a low-cost base. Located roughly 18–20 km east of the historic center in the Tababela area, travel times to central Quito can vary from about 30–60 minutes depending on traffic and time of day. Ground connections typically include taxis and ride-hailing services (often 25–40 minutes and mid-range fares), airport shuttles and private transfers, while public buses provide a lower-cost but slower option. The airport is modern and convenient for international connections, though road congestion and altitude-related weather can occasionally affect comfort and punctuality.
What is the cheapest price for flights from Quito to Panama City?
The cheapest flight ticket from Quito to Panama City according to data for the last 48 hours costs $222
When is the best time to buy air tickets on the route Quito — Panama City?
Often the best time to buy tickets from Quito to Panama City is 2 months before departure.
When is the cheapest time of year to fly from Quito to Panama City?
Based on statistics over the past years, the lowest prices for flights from Quito to Panama City can be found flying in these months: January, March, February.
How long does it take to fly from Quito to Panama City?
The fastest flights from Quito to Panama City start from 7 hours 30 minutes in the air.
Which airline can fly direct from Quito to Panama City?
The following airlines operate direct flights on the route Quito — Panama City: Copa Airlines
Tocumen International (PTY) is Panama City’s main international gateway and a regional hub for connecting flights across the Americas; it typically handles major carriers and full-service airlines, with some low-cost options on certain routes. The airport sits about 24 km (roughly 30–40 minutes) east of downtown Panama City by road; options to the city include taxi and ride-hail services (about 25–40 USD typical), airport shuttles and private transfers, plus occasional public buses for a lower-cost alternative. Pros: efficient transfer facilities, multiple lounges and duty-free shopping. Cons: busy peak periods, and fares and transfer times can vary with traffic. For low-cost or domestic travel, smaller regional airfields serve limited routes.
