Flaut.Travel was designed and developed by a team dedicated to making the process of searching, comparing and booking airline tickets as easy and convenient as possible. Our service helps travelers to find and buy the cheapest flights from Sao Paulo to Santa Cruz. We have connected more than 40 airlines and airline ticketing agencies to help you find the most suitable and affordable flight option.
The cost of a one-way flight from Sao Paulo to Santa Cruz ranges from $99 (September 2026) to $132 (October 2026). On average, the ticket price is about $121–$264.
A non-stop flight is the most convenient and comfortable way to fly from Sao Paulo to Santa Cruz, despite the fact that sometimes flights with transfers can cost significantly less.
The only airline operating direct flights from Sao Paulo to Santa Cruz is Boliviana de Aviación. Flights operate every day.
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Answers to questions about the route that travelers are most interested in.
We keep tight track on airlines' pre-holidays sales and other special offers occurences all the time to let you save maximum amount of funds while traveling to your family or just going out on vacation.
Flight costs from Sao Paulo to Santa Cruz climb toward the middle of the period, then start to drop. By choosing the right dates, you can save noticeably.
Prices rise from September 2026 to October 2026 (+34%), then decline from July 2026 to September 2026 (25%). The cheapest tickets are in July 2026–September 2026 (averaging $115), while the priciest are in September 2026–October 2026 ($116).
For savings, plan your flight for July 2026–September 2026 — you could save up to 0%. Try to avoid September 2026–October 2026 when possible: prices are at their highest then.
Price spread on this route is 12.9%. Costs depend heavily on the season, so flexibility in choosing your departure month is especially valuable here.
Boliviana de Aviación
Every day
starting at $134
Sao Paulo — Santa Cruz
07/21/2026
Departure
Direct flight
G37638
starting at $216
Sao Paulo — Santa Cruz
10/30/2026
Departure
Direct flight
OB735
starting at $132
Sao Paulo — Santa Cruz
07/31/2026
Departure
Direct flight
OB739
starting at $131
starting at $136
starting at $131
Flights from Sao Paulo to Santa Cruz are operated by several airlines — Gol Transportes Aéreos and Boliviana de Aviación. This allows passengers to flexibly choose flights based on departure time, cost, and additional services. The minimum ticket price starts at $131, making this destination accessible to travelers with different budgets. We help compare all available options in real time, so you can book tickets at the best value for money. The service ensures transparent search and lets you book affordable flights in just a few clicks.
The cheapest flight ticket from Sao Paulo to Santa Cruz according to data for the last 48 hours costs $131
Often the best time to buy tickets from Sao Paulo to Santa Cruz is 2 months before departure.
Based on statistics over the past years, the lowest prices for flights from Sao Paulo to Santa Cruz can be found flying in these months: September, July, October.
The fastest flights from Sao Paulo to Santa Cruz start from 2 hours 50 minutes in the air.
The following airlines operate direct flights on the route Sao Paulo — Santa Cruz: Gol Transportes Aéreos, Boliviana de Aviación
The cheapest one-way flight from Sao Paulo to Santa Cruz departs on 07/31/2026, is operated by Boliviana de Aviación and costs $131
The cheapest roundtrip flight from Sao Paulo to Santa Cruz departs on 07/28/2026, is operated by Gol Transportes Aéreos and costs $302
Fastest flight from Sao Paulo to Santa Cruz takes 2h 50m
There are direct flights on this route 2 days a week: Tu and Fr
The distance between Sao Paulo and Santa Cruz is 1836km (1138 miles). The average flight duration is 2h 50m. There are 4 direct flights from Sao Paulo to Santa Cruz. The time difference between Sao Paulo and Santa Cruz is 1h. Flights from Sao Paulo begin at 9:05 AM. The latest flight from Sao Paulo departs at 2:00 PM
Sao Paulo is served mainly by two airports with distinct roles. São Paulo–Guarulhos (GRU) is the city’s primary international gateway and a hub for full-service carriers; it typically handles long-haul and regional flights and can be pricier than domestic options. Located about 25–35 km northeast of downtown, travel by airport bus or taxi can take 30–60 minutes depending on traffic, with express bus fares and ride-share/taxi costs varying by provider. Congonhas (CGH) functions as the busy domestic/business airport closer to the city center (around 8–10 km), usually favored by budget and regional carriers for short-haul routes; transfers to central areas are often 15–30 minutes by taxi or metro+bus, generally cheaper but can be crowded at peak times. Pros: GRU offers extensive international connections and more amenities; CGH is convenient for quick city access. Cons: GRU journeys can be longer and affected by traffic; CGH has limited long-haul options and can be noisy and busy.
Viru Viru International Airport (VVI) is Santa Cruz’s main international gateway and typically serves as Bolivia’s busiest long-haul and regional hub. Expect a mix of full-service and low-cost carriers operating scheduled flights across South America and to a few international destinations; fares can be competitive compared with smaller domestic-only fields. The airport sits roughly 20–22 km north-west of the city center, with travel options including taxis (30–45 minutes, fares usually moderate), shared shuttles and occasional bus services (longer but cheaper). Pros: more flight choices and basic passenger facilities; cons: the transfer to central Santa Cruz can take time and be affected by traffic.
We couldn't find any special offers for flights from Sao Paulo to Santa Cruz