Cheap Flights from Sao Paulo to Santa Cruz — $133

Flights from Sao Paulo to Santa Cruz are operated by several airlines — Boliviana de Aviación and Gol Transportes Aéreos. This allows passengers to flexibly choose flights based on departure time, cost, and additional services. The minimum ticket price starts at $133, making this destination accessible to travelers with different budgets. We help compare all available options in real time, so you can book tickets at the best value for money. The service ensures transparent search and lets you book affordable flights in just a few clicks.

Fly direct from São Paulo to Santa Cruz for the fastest, most convenient way to reach Bolivia’s vibrant heart—no layovers, less hassle, and more time to enjoy your trip. While connecting flights can sometimes be cheaper, choosing a nonstop gives you added comfort and valuable hours back in your itinerary, perfect for business or leisure travel.

Sao Paulo is served mainly by two airports with distinct roles. São Paulo–Guarulhos (GRU) is the city’s primary international gateway and a hub for full-service carriers; it typically handles long-haul and regional flights and can be pricier than domestic options. Located about 25–35 km northeast of downtown, travel by airport bus or taxi can take 30–60 minutes depending on traffic, with express bus fares and ride-share/taxi costs varying by provider. Congonhas (CGH) functions as the busy domestic/business airport closer to the city center (around 8–10 km), usually favored by budget and regional carriers for short-haul routes; transfers to central areas are often 15–30 minutes by taxi or metro+bus, generally cheaper but can be crowded at peak times. Pros: GRU offers extensive international connections and more amenities; CGH is convenient for quick city access. Cons: GRU journeys can be longer and affected by traffic; CGH has limited long-haul options and can be noisy and busy.

Viru Viru International Airport (VVI) is Santa Cruz’s main international gateway and typically serves as Bolivia’s busiest long-haul and regional hub. Expect a mix of full-service and low-cost carriers operating scheduled flights across South America and to a few international destinations; fares can be competitive compared with smaller domestic-only fields. The airport sits roughly 20–22 km north-west of the city center, with travel options including taxis (30–45 minutes, fares usually moderate), shared shuttles and occasional bus services (longer but cheaper). Pros: more flight choices and basic passenger facilities; cons: the transfer to central Santa Cruz can take time and be affected by traffic.