starting at $173
starting at $195
starting at $209
starting at $323
starting at $327
Compare airlines, prices, and flight durations for your trip
Flaut.Travel was designed and developed by a team dedicated to making the process of searching, comparing and booking airline tickets as easy and convenient as possible. Our service helps travelers to find and buy the cheapest flights from Santiago to Santa Cruz. We have connected more than 40 airlines and airline ticketing agencies to help you find the most suitable and affordable flight option.
A non-stop flight is the most convenient and comfortable way to fly from Santiago to Santa Cruz, despite the fact that sometimes flights with transfers can cost significantly less.
A direct flight is the easiest way to get to your destination. The following airlines operate non-stop flights from Santiago to Santa Cruz:
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Answers to questions about the route that travelers are most interested in.
We keep tight track on airlines' pre-holidays sales and other special offers occurences all the time to let you save maximum amount of funds while traveling to your family or just going out on vacation.
The route Santiago — Santa Cruz is served by many carriers — 5 in total, including Aerolineas Argentinas, LATAM Chile, Avianca, Hesa Airlines, and Sky Airline. This gives passengers wide opportunities: from finding the lowest fare (from $173) to selecting flights by schedule or service class. Our service aggregates data from multiple booking systems so you can compare offers in one place. This saves time and money: no need to check dozens of sites — just pick the right option and book online.
starting at $173
starting at $195
starting at $209
starting at $323
starting at $327
There appear to be no non-stop flights from Santiago to Santa Cruz at this time.... Well, or something went wrong on our side and we couldn't find anything
Unable to find information about the schedule of direct flights from
We couldn't find any special offers for flights from Santiago to Santa Cruz
The cheapest flight ticket from Santiago to Santa Cruz according to data for the last 48 hours costs $173
Often the best time to buy tickets from Santiago to Santa Cruz is 2 months before departure.
The fastest flights from Santiago to Santa Cruz start from 4 hours 57 minutes in the air.
The following airlines operate direct flights on the route Santiago — Santa Cruz:
We carefully collect statistics on the search and pricing of airlines and, based on these data, we make an assumption about future prices. Thus, you can better understand which season is the cheapest to fly from Santiago to Santa Cruz
The cheapest one-way flight from Santiago to Santa Cruz departs on 08/21/2026, is operated by Aerolineas Argentinas and costs $173
The cheapest roundtrip flight from Santiago to Santa Cruz departs on 03/01/2026, is operated by LATAM Chile and costs $389
Fastest flight from Santiago to Santa Cruz takes 4h 57m
There are no direct flights on this route.
The distance between Santiago and Santa Cruz is 1886km (1169 miles). There are 4 direct flights from Santiago to Santa Cruz. Santiago and Santa Cruz are in the same time zone. Flights from Santiago begin at 4:33 AM. The latest flight from Santiago departs at 1:10 PM