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A direct flight is the easiest way to get to your destination. The following airlines operate non-stop flights from Santiago to Santa Cruz:
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Answers to questions about the route that travelers are most interested in.
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Unable to find information about the schedule of direct flights from
Flaut.Travel was designed and developed by a team dedicated to making the process of searching, comparing and booking airline tickets as easy and convenient as possible. Our service helps travelers to find and buy the cheapest flights from Santiago to Santa Cruz. We have connected more than 40 airlines and airline ticketing agencies to help you find the most suitable and affordable flight option.
There appear to be no non-stop flights from Santiago to Santa Cruz at this time.... Well, or something went wrong on our side and we couldn't find anything
starting at $169
starting at $203
The Santiago — Santa Cruz route is served by multiple airlines, including Aerolineas Argentinas and Avianca. This is convenient for those who want the best balance of price, schedule, and travel conditions. Tickets start from $169, and depending on season and promotions, even better deals may appear. With our service, you can easily compare available options and book tickets that match your plans. The variety of carriers allows flexible choices and comfortable travel without overpaying.
The cheapest flight ticket from Santiago to Santa Cruz according to data for the last 48 hours costs $169
Often the best time to buy tickets from Santiago to Santa Cruz is 2 months before departure.
Based on statistics over the past years, the lowest prices for flights from Santiago to Santa Cruz can be found flying in these months: August, March, February.
The fastest flights from Santiago to Santa Cruz start from 10 hours 35 minutes in the air.
The following airlines operate direct flights on the route Santiago — Santa Cruz:
In different months, ticket prices from Santiago to Santa Cruz vary: minimum — $170 (August 2026), maximum — $330 (February 2026). Typically, the flight costs $227–$510.
A non-stop flight is the most convenient and comfortable way to fly from Santiago to Santa Cruz, despite the fact that sometimes flights with transfers can cost significantly less.
The cheapest one-way flight from Santiago to Santa Cruz departs on 08/24/2026, is operated by Aerolineas Argentinas and costs $169
There is no information about the cheapest roundtrip flight from Santiago to Santa Cruz
Fastest flight from Santiago to Santa Cruz takes 10h 35m
There are no direct flights on this route.
The distance between Santiago and Santa Cruz is 1886km (1169 miles). There are 4 direct flights from Santiago to Santa Cruz. Santiago and Santa Cruz are in the same time zone. Flights from Santiago begin at 4:33 AM. The latest flight from Santiago departs at 1:10 PM
We couldn't find any special offers for flights from Santiago to Santa Cruz
