Cheap Flights from Santiago to Santa Cruz

Cheapest flights from Santiago to Santa Cruz

Flaut.Travel was designed and developed by a team dedicated to making the process of searching, comparing and booking airline tickets as easy and convenient as possible. Our service helps travelers to find and buy the cheapest flights from Santiago to Santa Cruz. We have connected more than 40 airlines and airline ticketing agencies to help you find the most suitable and affordable flight option.

Cheapest one way flight

$194

Aerolineas Argentinas

1 layover

1d 4h 20m

03/08/2027

The cheapest one-way flight from Santiago to Santa Cruz departs on 03/08/2027, is operated by Aerolineas Argentinas and costs $194

Cheapest round trip flight

$484

LATAM Chile

1 layover

18h 45m

03/26/2027

The cheapest roundtrip flight from Santiago to Santa Cruz departs on 03/26/2027, is operated by LATAM Chile and costs $484

The fastest flight

1d 4h 20m

Fastest flight from Santiago to Santa Cruz takes 1d 4h 20m

Direct flights

Several times a week

There are direct flights on this route 2 days a week: We and Th

Earliest flight

5:36 AM

Latest flight

2:25 AM

Direct flights count

3

Distance

1892km

Timezone difference

0h

The distance between Santiago and Santa Cruz is 1892km (1173 miles). There are 3 direct flights from Santiago to Santa Cruz. Santiago and Santa Cruz are in the same time zone. Flights from Santiago begin at 5:36 AM. The latest flight from Santiago departs at 2:25 AM

Remember that on average the ideal time to book flights is 2 months before departure!

Airfare from Santiago to Santa Cruz by month

In different months, ticket prices from Santiago to Santa Cruz vary: minimum — $177 (October 2026), maximum — $230 (January 2027). Typically, the flight costs $203–$230.

October 2026

Lowest price

on average:

$177

January 2027

Highest price

on average:

$230

Avg Price

Airlines operating on route

The Santiago — Santa Cruz route is served by multiple airlines, including Boliviana de Aviación, LATAM Chile, and Aerolineas Argentinas. This is convenient for those who want the best balance of price, schedule, and travel conditions. Tickets start from $194, and depending on season and promotions, even better deals may appear. With our service, you can easily compare available options and book tickets that match your plans. The variety of carriers allows flexible choices and comfortable travel without overpaying.

Boliviana de Aviación

starting at $196

LATAM Chile

starting at $380

Aerolineas Argentinas

starting at $194

Non-stop flights from Santiago to Santa Cruz

A non-stop flight is the most convenient and comfortable way to fly from Santiago to Santa Cruz, despite the fact that sometimes flights with transfers can cost significantly less.

Santiago — Santa Cruz

SCL — SRZ

02/03/2027

Departure

Direct flight

OB1723

starting at $196

Santiago — Santa Cruz

SCL — SRZ

02/04/2027

Departure

Direct flight

LA890

starting at $380

Schedule of direct flights from Santiago to Santa Cruz

There are most likely no direct flights on the Santiago — Santa Cruz route

Santiago airports overview

Arturo Merino Benitez Airport

•

SCL

23km

Santiago’s main international gateway serving Chile’s capital, offering domestic and international routes and connections across the country. Accessible to downtown by bus, taxi and highway links.

•

Santa Cruz airports overview

Viru Viru International Airport

•

VVI

17km

•

Frequently asked questions (FAQ)

Answers to questions about the route that travelers are most interested in.

What is the cheapest price for flights from Santiago to Santa Cruz?

The cheapest flight ticket from Santiago to Santa Cruz according to data for the last 48 hours costs $194

When is the best time to buy air tickets on the route Santiago — Santa Cruz?

Often the best time to buy tickets from Santiago to Santa Cruz is 2 months before departure.

When is the cheapest time of year to fly from Santiago to Santa Cruz?

Based on statistics over the past years, the lowest prices for flights from Santiago to Santa Cruz can be found flying in these months: October, January.

How long does it take to fly from Santiago to Santa Cruz?

The fastest flights from Santiago to Santa Cruz start from 4 hours 20 minutes in the air.

Which airline can fly direct from Santiago to Santa Cruz?

The following airlines operate direct flights on the route Santiago — Santa Cruz: Boliviana de Aviación, LATAM Chile

Special offers and sales on air tickets from Santiago to Santa Cruz

We keep tight track on airlines' pre-holidays sales and other special offers occurences all the time to let you save maximum amount of funds while traveling to your family or just going out on vacation.

We couldn't find any special offers for flights from Santiago to Santa Cruz

Alternative routes

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Cheapest one way flight

$194

Aerolineas Argentinas

1 layover

1d 4h 20m

03/08/2027

The cheapest one-way flight from Santiago to Santa Cruz departs on 03/08/2027, is operated by Aerolineas Argentinas and costs $194

Cheapest round trip flight

$484

LATAM Chile

1 layover

18h 45m

03/26/2027

The cheapest roundtrip flight from Santiago to Santa Cruz departs on 03/26/2027, is operated by LATAM Chile and costs $484

The fastest flight