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The cost of a one-way flight from Prague to Palermo ranges from $72 (February 2026) to $126 (May 2026). On average, the ticket price is about $99–$126.
A direct flight is the easiest way to get to your destination. The following airlines operate non-stop flights from Prague to Palermo:
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We keep tight track on airlines' pre-holidays sales and other special offers occurences all the time to let you save maximum amount of funds while traveling to your family or just going out on vacation.
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Looking for cheap flights from Prague to Palermo? Look no further! Our air ticket search website is here to save you both time and money. Prague, the capital of the Czech Republic, and Palermo, a vibrant city in Italy, await your exploration. Whether you're a history buff, a food lover, or simply seeking a sunny getaway, our website offers a wide array of affordable flight options for your convenience. With just a few clicks, you can compare prices from various airlines and find the best deal that suits your travel needs. Don't miss out on this opportunity to discover the rich culture and beautiful landscapes of Palermo. Start planning your trip now and secure your cheap flights from Prague to Palermo today!
There appear to be no non-stop flights from Prague to Palermo at this time.... Well, or something went wrong on our side and we couldn't find anything
Flights from Prague to Palermo are operated by several airlines — Ryanair, EasyJet, and LC Busre SAC. This allows passengers to flexibly choose flights based on departure time, cost, and additional services. The minimum ticket price starts at $69, making this destination accessible to travelers with different budgets. We help compare all available options in real time, so you can book tickets at the best value for money. The service ensures transparent search and lets you book affordable flights in just a few clicks.
The cheapest flight ticket from Prague to Palermo according to data for the last 48 hours costs $69
Often the best time to buy tickets from Prague to Palermo is 2 months before departure.
Based on statistics over the past years, the lowest prices for flights from Prague to Palermo can be found flying in these months: February, May.
The fastest flights from Prague to Palermo start from 5 hours 35 minutes in the air.
The following airlines operate direct flights on the route Prague — Palermo:
The cheapest one-way flight from Prague to Palermo departs on 01/17/2026, is operated by Ryanair and costs $69
The cheapest roundtrip flight from Prague to Palermo departs on 09/24/2026, is operated by EasyJet and costs $190
Fastest flight from Prague to Palermo takes 5h 35m
There are no direct flights on this route.
The distance between Prague and Palermo is 1327km (823 miles). Prague and Palermo are in the same time zone
Looking for a direct flight from Prague, Czech Republic to Palermo, Italy? Although there are currently no direct flights available on this route, fret not, as there are several alternative routes with convenient transfers. Fly from Prague to Rome or Milan, major Italian cities well-connected to Palermo. From either city, catch a connecting flight to Palermo and enjoy the picturesque island of Sicily. At our air ticket search website, we specialize in finding the best flight options for you. Simply enter your travel dates, and we'll provide you with a comprehensive list of available flights and transfer options. Whether you choose a direct flight or prefer the convenience of transfers, we guarantee a seamless booking experience at the best prices. Start planning your Prague to Palermo journey today and let us take care of your travel needs.
We couldn't find any special offers for flights from Prague to Palermo