Panama City — Santa Cruz
01/28/2027
Departure
Direct flight
CM127
starting at $725
Compare fares and flight options for Panama City — Santa Cruz. Prices can change; check availability when searching.
No monthly price comparison is available yet.
A non-stop flight is the most convenient and comfortable way to fly from Panama City to Santa Cruz, despite the fact that sometimes flights with transfers can cost significantly less.
Answers to questions about the route that travelers are most interested in.
We keep tight track on airlines' pre-holidays sales and other special offers occurences all the time to let you save maximum amount of funds while traveling to your family or just going out on vacation.
All airports
Panama City — Santa Cruz
01/28/2027
Departure
Direct flight
CM127
starting at $725
starting at $552
Copa Airlines
Th
starting at $725
The flight selection for Panama City — Santa Cruz features Copa Airlines. The lowest fare found is $552.
Direct offers from Panama City to Santa Cruz were found for these airlines: Copa Airlines: Th.
Weekdays and prices come from the offers found. This is not a complete schedule; availability and flight frequency can change.
The cheapest flight ticket from Panama City to Santa Cruz according to data for the last 48 hours costs $552
The lowest prices in the available monthly data for Panama City — Santa Cruz are in: January. Prices can change.
The shortest duration among the offers found for Panama City — Santa Cruz is 15 hours 29 minutes, including connections if present.
Direct flight offers from Panama City to Santa Cruz were found for: Copa Airlines
We couldn't find any special offers for flights from Panama City to Santa Cruz
The cheapest one-way flight from Panama City to Santa Cruz departs on 01/28/2027, is operated by Copa Airlines and costs $552
There is no information about the cheapest roundtrip flight from Panama City to Santa Cruz
Fastest flight from Panama City to Santa Cruz takes 15h 29m
Direct offers were found on these weekdays: Th.
The straight-line distance between Panama City and Santa Cruz is 3476km.
Direct-flight weekdays and the fastest option are based on the offers found.