Compare airlines, prices, and flight durations for your trip
In different months, ticket prices from Panama City to Madrid vary: minimum — $573 (March 2026), maximum — $573 (April 2026). Typically, the flight costs $573–$573.
A direct flight is the easiest way to get to your destination. The following airlines operate non-stop flights from Panama City to Madrid:
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Answers to questions about the route that travelers are most interested in.
We keep tight track on airlines' pre-holidays sales and other special offers occurences all the time to let you save maximum amount of funds while traveling to your family or just going out on vacation.
Looking for cheap flights from Panama City, Panama to Madrid, Spain? Look no further! Our air ticket search website offers the best deals on flights, saving you both time and money. With a click of a button, you can easily compare prices from various airlines and find the most affordable option for your travel needs. Madrid, the vibrant capital of Spain, awaits you with its rich history, stunning architecture, and mouthwatering cuisine. Whether you're planning a romantic getaway or a cultural adventure, our website ensures you find the cheapest flights available. Don't miss out on this opportunity to explore Madrid without breaking the bank. Visit our website now and book your affordable flight from Panama City to Madrid with ease. Start your journey today and experience the wonders of this incredible destination!
Looking for direct flights from Panama City, Panama to Madrid, Spain? Good news! There are direct flights available for this route. Enjoy a hassle-free journey without any layovers or transfers. Explore the vibrant culture of Madrid, indulge in delectable tapas, and visit iconic landmarks like the Royal Palace or Prado Museum. Have a fantastic time immersing yourself in this enchanting European city! However, if direct flights are not available for your preferred travel dates, fret not! There are alternative routes with convenient transfers. You can opt for connecting flights via major European airlines such as Air France, Iberia, or Lufthansa. These airlines often offer smooth connections in cities like Paris, Madrid, or Frankfurt. Rest assured, you will still be able to reach your destination and experience the magic of Madrid. For the best deals and options, search for your air tickets on our website. Book now and embark on your exciting journey from Panama City to Madrid!
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Welcome to Madrid, Spain! As a traveler, you have several airports to choose from when arriving in this vibrant city. Let's take a closer look at your options to ensure a smooth and convenient start to your journey. First up is Madrid-Barajas Airport, the main international gateway to the city. With countless airlines and flights, you're sure to find competitive prices. Located just 13 kilometers from downtown, a short taxi or bus ride will get you to your destination quickly. However, keep in mind that peak hours might increase travel time and costs. Popular carriers like Iberia and Air Europa operate from here, providing a prestigious experience. Next, we have Adolfo Suárez Madrid–Barajas Airport Terminal 4, designed to offer exceptional services and efficiency. This terminal handles a significant number of flights, focusing on long-haul routes. Enjoy impressive facilities during your layover, including shops, restaurants, and lounges. To reach the city center, hop on the convenient metro or hire a private transfer. Lastly, we present Torrejón Air Base, an alternative for low-cost airlines. Although located around 24 kilometers from Madrid, it offers competitive fares and is often chosen by budget-conscious travelers. Plan accordingly for the additional travel time and consider public transportation or shared shuttles, which reduce costs. In conclusion, Madrid's airports provide various advantages to suit every traveler's needs. From the extensive range of flights and prestigious carriers at Madrid-Barajas to the exceptional services at Terminal 4, you'll find convenience and quality. If budget is a priority, consider Torrejón Air Base, offering competitive fares at a distant location. So, whichever airport you choose, get ready to explore the wonders of Madrid! Book your air tickets now and start your Spanish adventure.
Panama City — Madrid
03/14/2026
Departure
Direct flight
UX56
starting at $1,065
Panama City — Madrid
03/16/2026
Departure
Direct flight
UX56
starting at $970
Panama City — Madrid
03/23/2026
Departure
Direct flight
UX56
starting at $725
Panama City — Madrid
04/02/2026
Departure
Direct flight
UX56
starting at $698
Panama City — Madrid
04/03/2026
Departure
Direct flight
UX56
starting at $603
Panama City — Madrid
04/19/2026
Departure
Direct flight
UX056
starting at $657
Panama City — Madrid
03/21/2026
Departure
Direct flight
UX56
starting at $884
Panama City — Madrid
04/14/2026
Departure
Direct flight
UX56
starting at $573
Panama City — Madrid
05/01/2026
Departure
Direct flight
UX56
starting at $627
The Panama City — Madrid route is served by multiple airlines, including Air Europa, Avianca, and Copa Airlines. This is convenient for those who want the best balance of price, schedule, and travel conditions. Tickets start from $573, and depending on season and promotions, even better deals may appear. With our service, you can easily compare available options and book tickets that match your plans. The variety of carriers allows flexible choices and comfortable travel without overpaying.
The cheapest flight ticket from Panama City to Madrid according to data for the last 48 hours costs $573
Often the best time to buy tickets from Panama City to Madrid is 2 months before departure.
Based on statistics over the past years, the lowest prices for flights from Panama City to Madrid can be found flying in these months: March, April.
The fastest flights from Panama City to Madrid start from 9 hours 35 minutes in the air.
The following airlines operate direct flights on the route Panama City — Madrid: Air Europa
We couldn't find any special offers for flights from Panama City to Madrid
The cheapest one-way flight from Panama City to Madrid departs on 03/13/2026, is operated by Avianca and costs $573
The cheapest roundtrip flight from Panama City to Madrid departs on 04/21/2026, is operated by Air Europa and costs $743
Fastest flight from Panama City to Madrid takes 9h 35m
There are direct flights on this route 6 days a week: Su, Mo, Tu, Th, Fr, and Sa
The distance between Panama City and Madrid is 8161km (5060 miles). There are 32 direct flights from Panama City to Madrid. The time difference between Panama City and Madrid is 6h. Flights from Panama City begin at 6:20 PM. The latest flight from Panama City departs at 9:30 PM