Panama City — Cali
11/26/2026
Departure
Direct flight
CM282
starting at $271
Compare fares and flight options for Panama City — Cali. Prices can change; check availability when searching.
A non-stop flight is the most convenient and comfortable way to fly from Panama City to Cali, despite the fact that sometimes flights with transfers can cost significantly less.
Answers to questions about the route that travelers are most interested in.
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Panama City — Cali
11/26/2026
Departure
Direct flight
CM282
starting at $271
starting at $271
starting at $199
Copa Airlines
Th
starting at $271
For Panama City — Cali, compare the offers found from Copa Airlines and Avianca. This selection includes 2 airlines, with fares from $199.
Direct offers from Panama City to Cali were found for these airlines: Copa Airlines: Th.
Weekdays and prices come from the offers found. This is not a complete schedule; availability and flight frequency can change.
No monthly price comparison is available yet.
The cheapest flight ticket from Panama City to Cali according to data for the last 48 hours costs $199
The shortest duration among the offers found for Panama City — Cali is 4 hours 55 minutes, including connections if present.
Direct flight offers from Panama City to Cali were found for: Copa Airlines
The cheapest one-way flight from Panama City to Cali departs on 11/26/2026, is operated by Avianca and costs $199
There is no information about the cheapest roundtrip flight from Panama City to Cali
Fastest flight from Panama City to Cali takes 4h 55m
Direct offers were found on these weekdays: Th.
The straight-line distance between Panama City and Cali is 698km.
Direct-flight weekdays and the fastest option are based on the offers found.
We couldn't find any special offers for flights from Panama City to Cali