Cheap Flights from Palermo to Brussels

Cheapest flights from Palermo to Brussels

Flaut.Travel was designed and developed by a team dedicated to making the process of searching, comparing and booking airline tickets as easy and convenient as possible. Our service helps travelers to find and buy the cheapest flights from Palermo to Brussels. We have connected more than 40 airlines and airline ticketing agencies to help you find the most suitable and affordable flight option.

Cheapest one way flight

$82

South African Express

1 layover

13h 40m

09/01/2026

The cheapest one-way flight from Palermo to Brussels departs on 09/01/2026, is operated by South African Express and costs $82

Cheapest round trip flight

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There is no information about the cheapest roundtrip flight from Palermo to Brussels

The fastest flight

13h 40m

Fastest flight from Palermo to Brussels takes 13h 40m

Direct flights

Once a week

There are direct flights on this route 1 day a week: Tu

Earliest flight

6:10 AM

Latest flight

8:20 PM

Direct flights count

11

Distance

1583km

Timezone difference

0h

The distance between Palermo and Brussels is 1583km (981 miles). There are 11 direct flights from Palermo to Brussels. Palermo and Brussels are in the same time zone. Flights from Palermo begin at 6:10 AM. The latest flight from Palermo departs at 8:20 PM

Remember that on average the ideal time to book flights is 2 months before departure!

Airfare from Palermo to Brussels by month

The cost of a one-way flight from Palermo to Brussels ranges from $67 (November 2026) to $144 (August 2026). On average, the ticket price is about $105–$144.

November 2026

Lowest price

on average:

$67

August 2026

Highest price

on average:

$144

Avg Price

Airlines operating on route

More than 4 airlines operate flights from Palermo to Brussels, including Ryanair, Mokulele Airlines, South African Express, and Vueling. This is a popular route, so passengers can choose tickets based on budget and preferences. Ticket prices start from $82, and our service lets you instantly compare all options. The variety of offers simplifies planning: you can choose budget fares or more comfortable options with baggage included or extra services. We help you find the best deals so your trip is cost-efficient.

Ryanair

starting at $155

Mokulele Airlines

starting at $122

South African Express

starting at $82

Vueling

starting at $88

Non-stop flights from Palermo to Brussels

A non-stop flight is the most convenient and comfortable way to fly from Palermo to Brussels, despite the fact that sometimes flights with transfers can cost significantly less.

Palermo — Brussels

PMO — BRU

09/01/2026

Departure

Direct flight

FR6268

starting at $155

Palermo — Brussels

PMO — BRU

09/08/2026

Departure

Direct flight

MW6268

starting at $122

Schedule of direct flights from Palermo to Brussels

There are most likely no direct flights on the Palermo — Brussels route

Palermo airports overview

Falcone-Borsellino Airport

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PMO

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Brussels airports overview

Brussels Airport

•

BRU

11km

Main international airport serving Brussels and Belgium, with extensive European and intercontinental routes and regular train and bus connections to the city centre.

Charleroi Brussels South Airport

•

CRL

45km

Serving Charleroi and the Brussels region, it handles mainly low-cost European routes and offers shuttle buses and rail links to Brussels and southern Belgium.

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Frequently asked questions (FAQ)

Answers to questions about the route that travelers are most interested in.

What is the cheapest price for flights from Palermo to Brussels?

The cheapest flight ticket from Palermo to Brussels according to data for the last 48 hours costs $82

When is the best time to buy air tickets on the route Palermo — Brussels?

Often the best time to buy tickets from Palermo to Brussels is 2 months before departure.

When is the cheapest time of year to fly from Palermo to Brussels?

Based on statistics over the past years, the lowest prices for flights from Palermo to Brussels can be found flying in these months: November, August.

How long does it take to fly from Palermo to Brussels?

The fastest flights from Palermo to Brussels start from 13 hours 40 minutes in the air.

Which airline can fly direct from Palermo to Brussels?

The following airlines operate direct flights on the route Palermo — Brussels: Ryanair, Mokulele Airlines

Special offers and sales on air tickets from Palermo to Brussels

We keep tight track on airlines' pre-holidays sales and other special offers occurences all the time to let you save maximum amount of funds while traveling to your family or just going out on vacation.

We couldn't find any special offers for flights from Palermo to Brussels

Alternative routes

Annaba ➜ Brussels•Bari ➜ Brussels•Cagliari ➜ Brussels•Catania ➜ Brussels•Foggia ➜ Brussels•Monastir ➜ Brussels•Pescara ➜ Brussels•Sfax ➜ Brussels•Tunis ➜ Brussels•Palermo ➜ Antwerp•Palermo ➜ Liege•Palermo ➜ Lille•Palermo ➜ Maastricht

•••••••••••••••••••

Cheapest one way flight

$82

South African Express

1 layover

13h 40m

09/01/2026

The cheapest one-way flight from Palermo to Brussels departs on 09/01/2026, is operated by South African Express and costs $82

Cheapest round trip flight

—

There is no information about the cheapest roundtrip flight from Palermo to Brussels

The fastest flight