Schedule of direct flights from Medellin to Santiago
A direct flight is the easiest way to get to your destination. The following airlines operate non-stop flights from Medellin to Santiago:
Medellin airports overview
Santiago airports overview
Frequently asked questions (FAQ)
Answers to questions about the route that travelers are most interested in.
Special offers and sales on air tickets from Medellin to Santiago
We keep tight track on airlines' pre-holidays sales and other special offers occurences all the time to let you save maximum amount of funds while traveling to your family or just going out on vacation.
Alternative routes
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Cheapest one way flight
$302
Copa Airlines
1 transfer
13h 40m
02/22/2025
The cheapest one-way flight from Medellin to Santiago departs on 02/22/2025, is operated by Copa Airlines and costs $302
Cheapest round trip flight
$445
Jatayu Airlines
1 transfer
18h 1m
09/13/2025
The cheapest roundtrip flight from Medellin to Santiago departs on 09/13/2025, is operated by Jatayu Airlines and costs $445
The fastest flight
6h 8m
Fastest flight from Medellin to Santiago takes 6h 8m
Direct flights
Once a week
There are direct flights on this route 1 day a week: Su
Earliest flight
1:13 PM
Latest flight
5:50 PM
Average flight duration
10h 25m
Direct flights count
10
Distance
4440km
Timezone difference
1h
The distance between Medellin and Santiago is 4440km (2753 miles).The average flight duration is 10h 25m.There are 10 direct flights from Medellin to Santiago.The time difference between Medellin and Santiago is 1h .Flights from Medellin begin at 1:13 PM.The latest flight from Medellin departs at 5:50 PM.
Unable to find information about the schedule of direct flights from
March 2025
Lowest price
on average:
$213
Flaut.Travel was designed and developed by a team dedicated to making the process of searching, comparing and booking airline tickets as easy and convenient as possible. Our service helps travelers to find and buy the cheapest flights from Medellin to Santiago. We have connected more than 40 airlines and airline ticketing agencies to help you find the most suitable and affordable flight option.
We carefully collect statistics on the search and pricing of airlines and, based on these data, we make an assumption about future prices. Thus, you can better understand which season is the cheapest to fly from Medellin to Santiago
Below you will find a list of airlines operating flights on the Medellin — Santiago route and the starting prices for flights of each specific airline on it.
A direct flight is the most convenient and comfortable way to fly from Medellin to Santiago, despite the fact that sometimes flights with transfers can cost significantly less.
