Cheap Flights from Medellin to Panama City — $163

Medellín is served by two main airports with distinct roles. José María Córdova International (MDE) is the primary international gateway, typically handling most long-haul and full-service carriers and often showing higher fares than the city airport; it sits about 35 km east of downtown in Rionegro. Travel to the city center usually takes 40–60 minutes by taxi or shuttle, with fares commonly ranging from modest to mid-level depending on traffic and service; there are also occasional airport buses. Olaya Herrera (EOH) is a smaller domestic and regional airport closer to the city—roughly 5 km from central Medellín—commonly used by budget and regional operators and can be quicker and cheaper for short hops. Ground connections from EOH include taxis and short transfer times of 15–25 minutes; public bus options may be limited. Pros: MDE offers wider international connectivity and more airline choices, while EOH is more convenient for rapid access to central neighborhoods. Cons: MDE’s distance can mean extra transfer time and potential higher costs, and EOH has fewer long-haul options and limited amenities compared with a larger international hub.

Fly nonstop from Medellín to Panama City for the quickest, most convenient way to bridge Colombia and Panama—less time in transit and more time exploring. While connecting options can sometimes be cheaper, choosing a direct flight saves hours and reduces hassle for a more comfortable trip, perfect for business or a weekend getaway.

Tocumen International (PTY) is Panama City’s main international gateway and regional hub, typically serving full-service carriers and major Latin American and North American airlines alongside some low-cost options. Located about 24 km (roughly 30–40 minutes by car) from central Panama City, it’s commonly reached by taxis, app rides, and occasional airport shuttle buses; expect fares to vary with traffic and service level. For budget travelers, smaller domestic terminals around the city handle regional flights and charter services. Pros: broad international connectivity and modern facilities; cons: peak-hour congestion and a longer transfer into the city compared with inner-city airports. Public bus options are cheaper but slower, while taxis offer faster, more comfortable transfers.

The route Medellin — Panama City is served by several airlines: Copa Airlines and Avianca. This gives passengers more freedom in choosing flights. You can consider not only the price but also schedules, baggage policies, and onboard service. Our service compares all offers so you can find tickets from $163 and choose the most convenient option. Thanks to airline competition, you may also find promotional fares or special offers, helping you save even more. Plan your trip in advance and choose the best flights without overpaying.

The minimum one-way ticket price from Medellin to Panama City is $179 (February 2026), while the maximum is $189 (January 2026). On average, a ticket costs $182–$369.