When is the cheapest time of year to fly from Medellin to Guayaquil?

Based on statistics over the past years, the lowest prices for flights from Medellin to Guayaquil can be found flying in these months: .

Cheap Flights from Medellin to Guayaquil

Cheapest flights from Medellin to Guayaquil

Flaut.Travel was designed and developed by a team dedicated to making the process of searching, comparing and booking airline tickets as easy and convenient as possible. Our service helps travelers to find and buy the cheapest flights from Medellin to Guayaquil. We have connected more than 40 airlines and airline ticketing agencies to help you find the most suitable and affordable flight option.

Cheapest one way flight

$181

Copa Airlines

1 transfer

5h 35m

02/28/2026

The cheapest one-way flight from Medellin to Guayaquil departs on 02/28/2026, is operated by Copa Airlines and costs $181

Cheapest round trip flight

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There is no information about the cheapest roundtrip flight from Medellin to Guayaquil

The fastest flight

2 hours

Fastest flight from Medellin to Guayaquil takes 2 hours

Direct flights

Once a week

There are direct flights on this route 1 day a week: Mo

Earliest flight

4:10 PM

Latest flight

6:25 PM

Direct flights count

4

Distance

1047km

Timezone difference

0h

The distance between Medellin and Guayaquil is 1047km (649 miles). There are 4 direct flights from Medellin to Guayaquil. Medellin and Guayaquil are in the same time zone. Flights from Medellin begin at 4:10 PM. The latest flight from Medellin departs at 6:25 PM

Remember that on average the ideal time to book flights is 2 months before departure!

Airfare from Medellin to Guayaquil by month

We carefully collect statistics on the search and pricing of airlines and, based on these data, we make an assumption about future prices. Thus, you can better understand which season is the cheapest to fly from Medellin to Guayaquil

Avg Price

Airlines operating on route

Flights from Medellin to Guayaquil are operated by several airlines — Avianca, Copa Airlines, and B&H Airlines. This allows passengers to flexibly choose flights based on departure time, cost, and additional services. The minimum ticket price starts at $181, making this destination accessible to travelers with different budgets. We help compare all available options in real time, so you can book tickets at the best value for money. The service ensures transparent search and lets you book affordable flights in just a few clicks.

Avianca

Starting at $188

Copa Airlines

Starting at $181

B&H Airlines

Starting at $199

Direct Flights from Medellin to Guayaquil

A direct flight is the most convenient and comfortable way to fly from Medellin to Guayaquil, despite the fact that sometimes flights with transfers can cost significantly less.

Medellin — Guayaquil

MDE — GYE

02/09/2026

Departure

Direct flight

AV8399

Starting at $254

Schedule of direct flights from Medellin to Guayaquil

A direct flight is the easiest way to get to your destination. The following airlines operate non-stop flights from Medellin to Guayaquil:

Unable to find information about the schedule of direct flights from

Medellin airports overview

Enrique Olaya Herrera Airport

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EOH

3km

Small urban airport in Medellín, Colombia, handling mainly domestic and regional flights and general aviation; convenient for access to the city center and nearby neighborhoods.

Jose Maria Cordova International Airport

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MDE

18km

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Guayaquil airports overview

Jose Joaquin de Olmedo Airport

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GYE

Primary international airport serving Guayaquil, Ecuador, handling domestic and international flights; main gateway for travel to the coastal region and Galápagos-bound connections.

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Frequently asked questions (FAQ)

Answers to questions about the route that travelers are most interested in.

How much is the cheapest flight ticket from Medellin to Guayaquil?

The cheapest flight ticket from Medellin to Guayaquil according to data for the last 48 hours costs $181

When is the best time to buy air tickets on the route Medellin — Guayaquil?

Often the best time to buy tickets from Medellin to Guayaquil is 2 months before departure.

How long does it take to fly from Medellin to Guayaquil?

The fastest flights from Medellin to Guayaquil start from 2 hours in the air.

Which airline can fly direct from Medellin to Guayaquil?

The following airlines operate direct flights on the route Medellin — Guayaquil: Avianca

Special offers and sales on air tickets from Medellin to Guayaquil

We keep tight track on airlines' pre-holidays sales and other special offers occurences all the time to let you save maximum amount of funds while traveling to your family or just going out on vacation.

We couldn't find any special offers for flights from Medellin to Guayaquil

Alternative routes

Apartado ➜ Guayaquil•Armenia ➜ Guayaquil•Bucaramanga ➜ Guayaquil•Bogota ➜ Guayaquil•Cartago ➜ Guayaquil•Barrancabermeja ➜ Guayaquil•Ibague ➜ Guayaquil•Manizales ➜ Guayaquil•Pereira ➜ Guayaquil•Quibdo ➜ Guayaquil•Medellin ➜ Chiclayo•Medellin ➜ Cuenca•Medellin ➜ Esmeraldas•Medellin ➜ Ipiales•Medellin ➜ Loja•Medellin ➜ Manta•Medellin ➜ Piura•Medellin ➜ Pasto•Medellin ➜ Quito

•••••••••••••••••••

Cheapest one way flight

$181

Copa Airlines

1 transfer

5h 35m

02/28/2026

The cheapest one-way flight from Medellin to Guayaquil departs on 02/28/2026, is operated by Copa Airlines and costs $181

Cheapest round trip flight

—

There is no information about the cheapest roundtrip flight from Medellin to Guayaquil

The fastest flight