Helping travelers to find the best flight offers
Fly from Istanbul to Santa Cruz with confidence—our search scans over 700 airlines, 50+ agencies and 5+ top booking systems to find the best prices, schedules and travel conditions for your trip. Compare options in seconds and pick the connection that fits your budget and timing, so you can focus on planning adventures in Bolivia.
The cost of a one-way flight from Istanbul to Santa Cruz ranges from $544 (December 2025) to $756 (June 2026). On average, the ticket price is about $631–$1,350.
A direct flight is the easiest way to get to your destination. The following airlines operate non-stop flights from Istanbul to Santa Cruz:
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We keep tight track on airlines' pre-holidays sales and other special offers occurences all the time to let you save maximum amount of funds while traveling to your family or just going out on vacation.
The cheapest one-way flight from Istanbul to Santa Cruz departs on 12/31/2025, is operated by Air Europa and costs $544
There is no information about the cheapest roundtrip flight from Istanbul to Santa Cruz
Fastest flight from Istanbul to Santa Cruz takes 19h 40m
There are no direct flights on this route.
The distance between Istanbul and Santa Cruz is 11456km (7103 miles). The time difference between Istanbul and Santa Cruz is 7h
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More than 5 airlines operate flights from Istanbul to Santa Cruz, including Air Europa, Wizz Air, Pegasus Airlines, Valuair, and Ethiopian Airlines. This is a popular route, so passengers can choose tickets based on budget and preferences. Ticket prices start from $544, and our service lets you instantly compare all options. The variety of offers simplifies planning: you can choose budget fares or more comfortable options with baggage included or extra services. We help you find the best deals so your trip is cost-efficient.
The cheapest flight ticket from Istanbul to Santa Cruz according to data for the last 48 hours costs $544
Often the best time to buy tickets from Istanbul to Santa Cruz is 2 months before departure.
Based on statistics over the past years, the lowest prices for flights from Istanbul to Santa Cruz can be found flying in these months: December, February, June.
The fastest flights from Istanbul to Santa Cruz start from 19 hours 40 minutes in the air.
The following airlines operate direct flights on the route Istanbul — Santa Cruz:
Istanbul Airport (IST) is Turkey’s main international gateway and a large hub for full-service carriers, especially Turkish Airlines, and increasingly used by many global airlines for long-haul connections. It’s positioned on the city’s European side, roughly 35–55 km from central districts depending on route, with travel times typically 35–60 minutes by taxi or 40–60 minutes by Havaist or municipal buses; fares for airport buses are usually modest while taxis can be substantially more. The airport is modern and spacious with extensive dining and shopping, making it convenient for transfers, though longer walking distances and occasional peak-hour traffic can add time and complexity. Sabiha Gökçen International Airport (SAW) serves many low-cost and regional carriers and is commonly used for budget and domestic flights to/from Istanbul’s Asian side. It sits about 35–45 km from central European-side neighborhoods but is closer to many Asian-side districts, with typical transfer times of 30–60 minutes by car depending on traffic; public options include Havatas/Havaist-like shuttles, buses, and occasional metro links with affordable fares. SAW can be a cost-effective pick and often features quicker check-ins for budget airlines, though it may involve longer road travel from some city centers and fewer high-end transfer amenities compared with the larger hub.
Skip the layovers and fly nonstop from Istanbul to Santa Cruz for the fastest, most convenient way to reach Bolivia’s vibrant lowland city — perfect when you want to maximize time on the ground. While connecting options can sometimes be cheaper, a direct flight saves hours and reduces hassle, making your trip more comfortable from departure to arrival.
Viru Viru International (VVI), located about 18–22 km northeast of downtown Santa Cruz, functions as Bolivia’s main international gateway for the region and typically handles most long-haul and regional flights. Expect a mix of flag-carriers and low-cost/regional airlines operating here, with fares that can be relatively higher for direct international legs but competitive on domestic sectors. Ground transfers include taxis (roughly 25–40 minutes, fares usually in a modest range), airport shuttles and private transfers; there can also be limited public bus options taking longer. Pros: straightforward international connections and modern facilities; cons: distance from the center and occasional traffic delays on the access road. There is also the smaller El Trompillo for charter and limited regional services, nearer the city but with fewer scheduled options.
We couldn't find any special offers for flights from Istanbul to Santa Cruz