Helping travelers to find the best flight offers
Find great deals from Cancun to Santiago by searching over 700 airlines, more than 50 agencies, and 5+ top booking systems to compare prices, schedules, and travel conditions in one go. Whether you want the fastest connection or the best fare, our fast search helps you pick the ideal flight and book with confidence.
Fly nonstop from Cancun to Santiago for the quickest, most convenient way to link Mexico’s Caribbean beaches with Chile’s vibrant capital — fewer hassles, no layovers, and more time to enjoy your trip. While connecting flights can sometimes be cheaper, a direct flight saves hours and delivers a more comfortable, stress-free journey, perfect for maximizing your getaway or business schedule.
A direct flight is the easiest way to get to your destination. The following airlines operate non-stop flights from Cancun to Santiago:
•
•
•
•
•
•
We keep tight track on airlines' pre-holidays sales and other special offers occurences all the time to let you save maximum amount of funds while traveling to your family or just going out on vacation.
The cheapest one-way flight from Cancun to Santiago departs on 03/25/2026, is operated by Avianca and costs $245
The cheapest roundtrip flight from Cancun to Santiago departs on 12/21/2025, is operated by Copa Airlines and costs $816
Fastest flight from Cancun to Santiago takes 13 hours
There are no direct flights on this route.
The distance between Cancun and Santiago is 6297km (3904 miles). There are 2 direct flights from Cancun to Santiago. The time difference between Cancun and Santiago is 1h. Flights from Cancun begin at 12:15 PM. The latest flight from Cancun departs at 12:15 PM
Flights from Cancun to Santiago are operated by several airlines — Avianca and Asian Air. This allows passengers to flexibly choose flights based on departure time, cost, and additional services. The minimum ticket price starts at $245, making this destination accessible to travelers with different budgets. We help compare all available options in real time, so you can book tickets at the best value for money. The service ensures transparent search and lets you book affordable flights in just a few clicks.
There appear to be no direct flights from Cancun to Santiago at this time.... Well, or something went wrong on our side and we couldn't find anything
Unable to find information about the schedule of direct flights from
Cancún International Airport (CUN) is Mexico’s main gateway for the Yucatán Peninsula and typically functions as a large international hub handling both full-service and low-cost carriers, with many seasonal charters. Flights here can often be competitively priced compared with smaller regional airports, especially outside peak holiday weeks. The airport sits about 16 km (roughly 20–30 minutes) north of downtown Cancún; regular options include shared shuttles and private transfers (about 15–30 USD per person), ADO buses (cheaper, about 1–5 USD, 25–45 minutes) and taxis (faster but pricier). Pros: extensive international connections and good tourist services; cons: can be crowded in high season and transfer times may lengthen due to traffic.
Arturo Merino Benítez Airport (SCL) serves as Chile’s main international gateway and the primary hub for full-service carriers like LATAM, while also handling several regional and low-cost operators. Located about 15 km northwest of downtown Santiago, transfer times by taxi or ride-share are typically 20–40 minutes depending on traffic; the dedicated commuter train and airport bus services can take 25–45 minutes with fares usually ranging from modest to moderate. SCL offers extensive international connections and full passenger amenities, though peak-hour congestion and occasional delays can affect comfort. For budget-conscious travelers, some low-cost flights may be cheaper but could use secondary terminals and fewer inclusive services.
We couldn't find any special offers for flights from Cancun to Santiago
The cheapest flight ticket from Cancun to Santiago according to data for the last 48 hours costs $245
Often the best time to buy tickets from Cancun to Santiago is 2 months before departure.
Based on statistics over the past years, the lowest prices for flights from Cancun to Santiago can be found flying in these months: January, November, February.
The fastest flights from Cancun to Santiago start from 13 hours in the air.
The following airlines operate direct flights on the route Cancun — Santiago:
The cost of a one-way flight from Cancun to Santiago ranges from $248 (January 2026) to $343 (February 2026). On average, the ticket price is about $292–$628.