Cali — Panama City
11/12/2026
Departure
Direct flight
CM370
starting at $334
Cali — Panama City
11/21/2026
Departure
Direct flight
CM308
starting at $335
Cali — Panama City
11/14/2026
Departure
Direct flight
CM842
starting at $337
Compare fares and flight options for Cali — Panama City. Prices can change; check availability when searching.
A non-stop flight is the most convenient and comfortable way to fly from Cali to Panama City, despite the fact that sometimes flights with transfers can cost significantly less.
Answers to questions about the route that travelers are most interested in.
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We carefully collect statistics on the search and pricing of airlines and, based on these data, we make an assumption about future prices. Thus, you can better understand which season is the cheapest to fly from Cali to Panama City
Cali — Panama City
11/12/2026
Departure
Direct flight
CM370
starting at $334
Cali — Panama City
11/21/2026
Departure
Direct flight
CM308
starting at $335
Cali — Panama City
11/14/2026
Departure
Direct flight
CM842
starting at $337
starting at $334
starting at $249
Copa Airlines
Th and Sa
starting at $334
The flight selection for Cali — Panama City includes offers from Copa Airlines and Avianca. Compare the featured carriers: the cheapest ticket found costs $249.
Direct offers from Cali to Panama City were found for these airlines: Copa Airlines: Th and Sa.
Weekdays and prices come from the offers found. This is not a complete schedule; availability and flight frequency can change.
The cheapest flight ticket from Cali to Panama City according to data for the last 48 hours costs $249
The shortest duration among the offers found for Cali — Panama City is 4 hours 45 minutes, including connections if present.
Direct flight offers from Cali to Panama City were found for: Copa Airlines
We couldn't find any special offers for flights from Cali to Panama City
The cheapest one-way flight from Cali to Panama City departs on 11/21/2026, is operated by Avianca and costs $249
The cheapest roundtrip flight from Cali to Panama City departs on 11/18/2026, is operated by Avianca and costs $374
Fastest flight from Cali to Panama City takes 4h 45m
Direct offers were found on these weekdays: Th and Sa.
The found offers from Cali to Panama City depart between 10:30 AM and 8:20 PM, in the origin city’s time zone. The straight-line distance between Cali and Panama City is 698km.
Direct-flight weekdays and the fastest option are based on the offers found.
Duration and departure times are based on found offers, not the full schedule. Times use the origin city’s time zone.