Compare airlines, prices, and flight durations for your trip
A direct flight is the easiest way to get to your destination. The following airlines operate non-stop flights from Brussels to San Francisco:
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Answers to questions about the route that travelers are most interested in.
We keep tight track on airlines' pre-holidays sales and other special offers occurences all the time to let you save maximum amount of funds while traveling to your family or just going out on vacation.
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In different months, ticket prices from Brussels to San Francisco vary: minimum — $536 (May 2026), maximum — $548 (September 2026). Typically, the flight costs $542–$548.
There appear to be no non-stop flights from Brussels to San Francisco at this time.... Well, or something went wrong on our side and we couldn't find anything
The Brussels — San Francisco route is served by multiple airlines, including Ryanair, Vueling, and TAP Portugal. This is convenient for those who want the best balance of price, schedule, and travel conditions. Tickets start from $511, and depending on season and promotions, even better deals may appear. With our service, you can easily compare available options and book tickets that match your plans. The variety of carriers allows flexible choices and comfortable travel without overpaying.
The cheapest flight ticket from Brussels to San Francisco according to data for the last 48 hours costs $511
Often the best time to buy tickets from Brussels to San Francisco is 2 months before departure.
Based on statistics over the past years, the lowest prices for flights from Brussels to San Francisco can be found flying in these months: May, September.
The fastest flights from Brussels to San Francisco start from 20 hours 40 minutes in the air.
The following airlines operate direct flights on the route Brussels — San Francisco:
The cheapest one-way flight from Brussels to San Francisco departs on 09/13/2026, is operated by Ryanair and costs $511
The cheapest roundtrip flight from Brussels to San Francisco departs on 09/16/2026, is operated by TAP Portugal and costs $780
Fastest flight from Brussels to San Francisco takes 20h 40m
There are no direct flights on this route.
The distance between Brussels and San Francisco is 8877km (5504 miles). The time difference between Brussels and San Francisco is 9h
Flaut.Travel was designed and developed by a team dedicated to making the process of searching, comparing and booking airline tickets as easy and convenient as possible. Our service helps travelers to find and buy the cheapest flights from Brussels to San Francisco. We have connected more than 40 airlines and airline ticketing agencies to help you find the most suitable and affordable flight option.
A non-stop flight is the most convenient and comfortable way to fly from Brussels to San Francisco, despite the fact that sometimes flights with transfers can cost significantly less.
We couldn't find any special offers for flights from Brussels to San Francisco