Cheap Flights from Santo Domingo to Medellin

Cheapest flights from Santo Domingo to Medellin

Flaut.Travel was designed and developed by a team dedicated to making the process of searching, comparing and booking airline tickets as easy and convenient as possible. Our service helps travelers to find and buy the cheapest flights from Santo Domingo to Medellin. We have connected more than 40 airlines and airline ticketing agencies to help you find the most suitable and affordable flight option.

Cheapest one way flight

$112

Aerorepublica

Direct flight

2h 28m

08/22/2026

The cheapest one-way flight from Santo Domingo to Medellin departs on 08/22/2026, is operated by Aerorepublica and costs $112

Cheapest round trip flight

$310

Asian Air

Direct flight

5h 2m

01/22/2027

The cheapest roundtrip flight from Santo Domingo to Medellin departs on 01/22/2027, is operated by Asian Air and costs $310

The fastest flight

2h 28m

Fastest flight from Santo Domingo to Medellin takes 2h 28m

Direct flights

Several times a week

There are direct flights on this route 6 days a week: Su, Mo, Tu, We, Fr, and Sa

Earliest flight

6:05 PM

Latest flight

6:05 PM

Direct flights count

1

Distance

1492km

Timezone difference

1h

The distance between Santo Domingo and Medellin is 1492km (925 miles). There are 1 direct flight from Santo Domingo to Medellin. The time difference between Santo Domingo and Medellin is 1h. Flights from Santo Domingo begin at 6:05 PM. The latest flight from Santo Domingo departs at 6:05 PM

Remember that on average the ideal time to book flights is 2 months before departure!

Airfare from Santo Domingo to Medellin by month

The minimum one-way ticket price from Santo Domingo to Medellin is $111 (December 2026), while the maximum is $167 (July 2026). On average, a ticket costs $119–$127.

December 2026

Lowest price

on average:

$111

July 2026

Highest price

on average:

$167

Avg Price

Price dynamics

Ticket prices for Santo Domingo — Medellin are higher at the start and end of the period but lowest in the middle. This creates a convenient window for booking at a reduced price.

Cheaper and more expensive periods

Prices fall from July 2026 to December 2026 (33%), then rise from June 2026 to July 2026 (+41%). The best period is August 2026–December 2026 ($112), the most expensive is June 2026–July 2026 ($143).

Best time to buy

The best time to buy is August 2026–December 2026, when prices are at their lowest. This can save you up to 22% compared to the expensive months (June 2026–July 2026).

Price predictability

Monthly price variation is 18.2%. On this route, your departure date noticeably affects the cost, and choosing wisely can lead to real savings.

Airlines operating on route

The route Santo Domingo — Medellin is served by several airlines: Asian Air, Aerorepublica, and Avianca. This gives passengers more freedom in choosing flights. You can consider not only the price but also schedules, baggage policies, and onboard service. Our service compares all offers so you can find tickets from $112 and choose the most convenient option. Thanks to airline competition, you may also find promotional fares or special offers, helping you save even more. Plan your trip in advance and choose the best flights without overpaying.

Asian Air

starting at $119

Aerorepublica

starting at $112

Avianca

starting at $133

Non-stop flights from Santo Domingo to Medellin

A non-stop flight is the most convenient and comfortable way to fly from Santo Domingo to Medellin, despite the fact that sometimes flights with transfers can cost significantly less.

Santo Domingo — Medellin

SDQ — MDE

06/28/2026

Departure

Direct flight

DM1736

starting at $183

Santo Domingo — Medellin

SDQ — MDE

07/06/2026

Departure

Direct flight

DM1734

starting at $171

Santo Domingo — Medellin

SDQ — MDE

08/09/2026

Departure

Direct flight

DM1736

starting at $175

Santo Domingo — Medellin

SDQ — MDE

06/09/2026

Departure

Direct flight

DM1738

starting at $195

Santo Domingo — Medellin

SDQ — MDE

06/10/2026

Departure

Direct flight

DM1738

starting at $213

Santo Domingo — Medellin

SDQ — MDE

06/12/2026

Departure

Direct flight

DM1738

starting at $204

Santo Domingo — Medellin

SDQ — MDE

06/13/2026

Departure

Direct flight

P57421

starting at $138

Santo Domingo — Medellin

SDQ — MDE

07/10/2026

Departure

Direct flight

DM1738

starting at $197

Santo Domingo — Medellin

SDQ — MDE

07/11/2026

Departure

Direct flight

DM1736

starting at $176

Santo Domingo — Medellin

SDQ — MDE

06/20/2026

Departure

Direct flight

DM1736

starting at $238

Schedule of direct flights from Santo Domingo to Medellin

There are most likely no direct flights on the Santo Domingo — Medellin route

Santo Domingo airports overview

La Isabela International Airport

•

JBQ

9km

Las Americas International Airport

•

SDQ

34km

Serving Santo Domingo, Dominican Republic, handling domestic and international flights with regular connections across the Caribbean and the Americas; convenient for access to the capital and nearby resort areas.

•

Medellin airports overview

Enrique Olaya Herrera Airport

•

EOH

3km

Small urban airport in Medellín, Colombia, handling mainly domestic and regional flights and general aviation; convenient for access to the city center and nearby neighborhoods.

Jose Maria Cordova International Airport

•

MDE

18km

•

Frequently asked questions (FAQ)

Answers to questions about the route that travelers are most interested in.

What is the cheapest price for flights from Santo Domingo to Medellin?

The cheapest flight ticket from Santo Domingo to Medellin according to data for the last 48 hours costs $112

When is the best time to buy air tickets on the route Santo Domingo — Medellin?

Often the best time to buy tickets from Santo Domingo to Medellin is 2 months before departure.

When is the cheapest time of year to fly from Santo Domingo to Medellin?

Based on statistics over the past years, the lowest prices for flights from Santo Domingo to Medellin can be found flying in these months: December, August, June.

How long does it take to fly from Santo Domingo to Medellin?

The fastest flights from Santo Domingo to Medellin start from 2 hours 28 minutes in the air.

Which airline can fly direct from Santo Domingo to Medellin?

The following airlines operate direct flights on the route Santo Domingo — Medellin: Asian Air, Aerorepublica

Special offers and sales on air tickets from Santo Domingo to Medellin

We keep tight track on airlines' pre-holidays sales and other special offers occurences all the time to let you save maximum amount of funds while traveling to your family or just going out on vacation.

We couldn't find any special offers for flights from Santo Domingo to Medellin

Alternative routes

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Cheapest one way flight

$112

Aerorepublica

Direct flight

2h 28m

08/22/2026

The cheapest one-way flight from Santo Domingo to Medellin departs on 08/22/2026, is operated by Aerorepublica and costs $112

Cheapest round trip flight

$310

Asian Air

Direct flight

5h 2m

01/22/2027

The cheapest roundtrip flight from Santo Domingo to Medellin departs on 01/22/2027, is operated by Asian Air and costs $310

The fastest flight