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Fly from Santa Cruz to La Paz with confidence — our search scans over 700 airlines, 50+ travel agencies and more than 5 top booking systems to surface the best prices, schedules and travel conditions for your trip. Compare options in seconds and book the flight that fits your budget and timing with ease.
The minimum one-way ticket price from Santa Cruz to La Paz is $94 (December 2025), while the maximum is $112 (January 2026). On average, a ticket costs $103–$216.
Fly direct from Santa Cruz to La Paz for the fastest, most convenient way to travel between Bolivia’s two major cities—no layovers, less hassle, and more time to enjoy your destination. While connecting flights can sometimes be cheaper, a nonstop trip saves hours and offers a more comfortable, stress-free journey worth the upgrade.
A direct flight is the easiest way to get to your destination. The following airlines operate non-stop flights from Santa Cruz to La Paz:
We keep tight track on airlines' pre-holidays sales and other special offers occurences all the time to let you save maximum amount of funds while traveling to your family or just going out on vacation.
The cheapest one-way flight from Santa Cruz to La Paz departs on 11/23/2025, is operated by Boliviana de Aviación and costs $94
The cheapest roundtrip flight from Santa Cruz to La Paz departs on 10/11/2025, is operated by Boliviana de Aviación and costs $170
Fastest flight from Santa Cruz to La Paz takes 1h 5m
There are direct flights on this route 2 days a week: Su and Tu
The distance between Santa Cruz and La Paz is 547km (339 miles). There are 79 direct flights from Santa Cruz to La Paz. Santa Cruz and La Paz are in the same time zone. Flights from Santa Cruz begin at 5:30 AM. The latest flight from Santa Cruz departs at 10:25 PM
Boliviana de Aviación
Every day
Starting at $301
El Alto International Airport (LPB) is La Paz’s main international gateway and typically functions as Bolivia’s high-altitude hub for both regional and a few long-haul connections. Airlines operating here tend to include national carriers and regional low-cost operators, so fares can range from budget-friendly to mid-tier depending on route and season. The airport sits well above the city at El Alto, roughly 30–45 minutes from central La Paz by road (traffic and altitude can affect travel time), with taxis, ride-hailing services and occasional shared minibuses as the usual options; expect fares to vary from modest to moderate. Pros: direct international links and modern facilities; cons: significant elevation and the taxi-dependent transfer to downtown can feel less convenient for first-time visitors.
Santa Cruz — La Paz
11/23/2025
Departure
Direct flight
OB669
Starting at $94
Santa Cruz — La Paz
12/28/2025
Departure
Direct flight
OB687
Starting at $94
Santa Cruz — La Paz
03/03/2026
Departure
Direct flight
OB663
Starting at $103
Santa Cruz — La Paz
07/21/2026
Departure
Direct flight
OB663
Starting at $107
Starting at $94
The route Santa Cruz — La Paz is served by a single airline — Boliviana de Aviación. This means that when planning your trip, you won’t need to spend time choosing between dozens of carriers: all flights are operated by one provider, which simplifies the booking process. Despite the limited choice, passengers can still plan ahead, select optimal departure dates, and buy tickets at the lowest price — from $94. Using our service, you can quickly compare available Boliviana de Aviación flights and book a seat in advance at a favorable rate.
The cheapest flight ticket from Santa Cruz to La Paz according to data for the last 48 hours costs $94
Often the best time to buy tickets from Santa Cruz to La Paz is 2 months before departure.
Based on statistics over the past years, the lowest prices for flights from Santa Cruz to La Paz can be found flying in these months: December, March, January.
The fastest flights from Santa Cruz to La Paz start from 1 hour 5 minutes in the air.
The following airlines operate direct flights on the route Santa Cruz — La Paz: Boliviana de Aviación
Viru Viru International (VVI) serves as Santa Cruz’s main international gateway and typically functions as the region’s premium hub, handling most long-haul and regional flights. It is commonly used by full-service carriers and several regional airlines, while a few low-cost operators may offer budget options. The airport sits roughly 18–20 km northwest of downtown Santa Cruz; road transfers usually take 20–40 minutes depending on traffic, with taxis and private shuttles commonly available and fares generally varying by operator. Local buses and occasional shared vans can be cheaper but slower. Pros: more flight choices and basic passenger services; cons: transfer time to the city and limited late-night public transport.
We couldn't find any special offers for flights from Santa Cruz to La Paz