Starting at $85
Starting at $124
Helping travelers to find the best flight offers
A direct flight is the easiest way to get to your destination. The following airlines operate non-stop flights from Panama City to Medellin:
We keep tight track on airlines' pre-holidays sales and other special offers occurences all the time to let you save maximum amount of funds while traveling to your family or just going out on vacation.
Starting at $85
Starting at $124
We carefully collect statistics on the search and pricing of airlines and, based on these data, we make an assumption about future prices. Thus, you can better understand which season is the cheapest to fly from Panama City to Medellin
Below you will find a list of airlines operating flights on the Panama City — Medellin route and the starting prices for flights of each specific airline on it.
A direct flight is the most convenient and comfortable way to fly from Panama City to Medellin, despite the fact that sometimes flights with transfers can cost significantly less.
Flaut.Travel was designed and developed by a team dedicated to making the process of searching, comparing and booking airline tickets as easy and convenient as possible. Our service helps travelers to find and buy the cheapest flights from Panama City to Medellin. We have connected more than 40 airlines and airline ticketing agencies to help you find the most suitable and affordable flight option.
Copa Airlines
Every day
Starting at $149
Avianca
Every day
Starting at $125
Panama City — Medellin
01/31/2025
Departure date
Direct flight
AV317
Starting at $185
Panama City — Medellin
02/01/2025
Departure date
Direct flight
AV323
Starting at $134
Panama City — Medellin
02/14/2025
Departure date
Direct flight
AV317
Starting at $184
Panama City — Medellin
02/15/2025
Departure date
Direct flight
AV323
Starting at $180
Panama City — Medellin
03/03/2025
Departure date
Direct flight
CM855
Starting at $135
Panama City — Medellin
03/04/2025
Departure date
Direct flight
AV317
Starting at $179
Panama City — Medellin
09/26/2025
Departure date
Direct flight
AV317
Starting at $122
The cheapest flight ticket from Panama City to Medellin according to data for the last 48 hours costs $122
Often the best time to buy tickets from Panama City to Medellin is 2 months before departure.
Based on statistics over the past years, the lowest prices for flights from Panama City to Medellin can be found flying in these months: February, January, April.
The fastest flights from Panama City to Medellin start from 1 hour 10 minutes in the air.
The following airlines operate direct flights on the route Panama City — Medellin: Avianca, Copa Airlines
The cheapest one-way flight from Panama City to Medellin departs on 09/26/2025, is operated by Avianca and costs $122
The cheapest roundtrip flight from Panama City to Medellin departs on 03/12/2025, is operated by Copa Airlines and costs $209
Fastest flight from Panama City to Medellin takes 1h 10m
There are direct flights on this route 4 days a week: Mo, Tu, Fr, and Sa
The distance between Panama City and Medellin is 531km (329 miles). The average flight duration is 1h 26m. There are 75 direct flights from Panama City to Medellin. Panama City and Medellin are in the same time zone. Flights from Panama City begin at 7:01 AM. The latest flight from Panama City departs at 9:27 PM.
We couldn't find any special offers for flights from Panama City to Medellin