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Cheapest flights from Panama City to Medellin
Flaut.Travel was designed and developed by a team dedicated to making the process of searching, comparing and booking airline tickets as easy and convenient as possible. Our service helps travelers to find and buy the cheapest flights from Panama City to Medellin. We have connected more than 40 airlines and airline ticketing agencies to help you find the most suitable and affordable flight option.
Remember that on average the ideal time to book flights is 2 months before departure!
A non-stop flight is the most convenient and comfortable way to fly from Panama City to Medellin, despite the fact that sometimes flights with transfers can cost significantly less.
Schedule of direct flights from Panama City to Medellin
Panama City airports overview
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Medellin airports overview
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Frequently asked questions (FAQ)
Answers to questions about the route that travelers are most interested in.
Special offers and sales on air tickets from Panama City to Medellin
We keep tight track on airlines' pre-holidays sales and other special offers occurences all the time to let you save maximum amount of funds while traveling to your family or just going out on vacation.
Alternative routes
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Cheapest one way flight
$142
Copa Airlines
Direct flight
1h 25m
10/28/2026
The cheapest one-way flight from Panama City to Medellin departs on 10/28/2026, is operated by Copa Airlines and costs $142
Cheapest round trip flight
$245
Copa Airlines
Direct flight
2h 53m
08/26/2026
The cheapest roundtrip flight from Panama City to Medellin departs on 08/26/2026, is operated by Copa Airlines and costs $245
The fastest flight
1h 25m
Fastest flight from Panama City to Medellin takes 1h 25m
Direct flights
Several times a week
There are direct flights on this route 2 days a week: Mo and Th
Earliest flight
6:49 AM
Latest flight
9:24 PM
Direct flights count
62
Distance
531km
Timezone difference
0h
The distance between Panama City and Medellin is 531km (329 miles). There are 62 direct flights from Panama City to Medellin. Panama City and Medellin are in the same time zone. Flights from Panama City begin at 6:49 AM. The latest flight from Panama City departs at 9:24 PM
October 2026
Lowest price
on average:
$142
September 2026
Highest price
on average:
$152
Avg Price
You can fly from Panama City to Medellin with Copa Airlines. It is the only carrier on this route, which makes the choice straightforward. Despite the lack of competition, ticket prices remain affordable: fares start from $142. Our service helps you track price changes, compare by dates, and select the most suitable flight. If you value stability and predictability, flying with Copa Airlines is a convenient solution. We make it easy to find good deals and ensure a comfortable booking process.
Tocumen International Airport (PTY) serves Panama City as the country’s primary international hub, handling most long-haul and regional flights and acting as a common connecting point in Central America. It’s typically used by full-service carriers and major regional airlines, while some low-cost carriers operate select routes. Tocumen sits about 24–28 km (roughly 30–45 minutes) from the historic Casco Viejo and downtown, with taxis, app rides and airport shuttles available; fares can range widely depending on service and traffic. Pros: modern terminal, many onward connections and decent passenger facilities. Cons: can be busy during peak times and transit times to the city vary with rush-hour congestion.
What is the cheapest price for flights from Panama City to Medellin?
The cheapest flight ticket from Panama City to Medellin according to data for the last 48 hours costs $142
When is the best time to buy air tickets on the route Panama City — Medellin?
Often the best time to buy tickets from Panama City to Medellin is 2 months before departure.
When is the cheapest time of year to fly from Panama City to Medellin?
Based on statistics over the past years, the lowest prices for flights from Panama City to Medellin can be found flying in these months: October, September.
How long does it take to fly from Panama City to Medellin?
The fastest flights from Panama City to Medellin start from 1 hour 25 minutes in the air.
Which airline can fly direct from Panama City to Medellin?
The following airlines operate direct flights on the route Panama City — Medellin: Copa Airlines
In different months, ticket prices from Panama City to Medellin vary: minimum — $142 (October 2026), maximum — $152 (September 2026). Typically, the flight costs $147–$152.
Medellín is served by two main airports with distinct roles. José María Córdova International (MDE) in Rionegro is the primary international gateway and a regional hub for full-service carriers, while Olaya Herrera (EOH) close to downtown typically handles domestic and regional flights, often favored by budget and regional operators. MDE sits roughly 35–40 km (about 45–60 minutes by road) from the city center; common transfers include taxis, private shuttles and intercity buses with fares usually higher than city transit. EOH is much closer—around 5–10 minutes or 3–5 km—reachable by taxi or bus at low cost. MDE can be more comfortable for long-haul connections and offers more amenities, but the longer transfer can add time and cost; EOH is convenient for quick domestic hops though facilities may be more basic.
We couldn't find any special offers for flights from Panama City to Medellin
