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The minimum one-way ticket price from Lisbon to Santiago is $513 (April 2026), while the maximum is $800 (December 2025). On average, a ticket costs $656–$800.
Fly direct from Lisbon to Santiago for the fastest, most convenient way to cross the Atlantic and start exploring Chile without long layovers. While connecting itineraries can sometimes be cheaper, a non‑stop flight saves hours and offers a more comfortable, hassle‑free journey—perfect for maximizing your time in Santiago.
A direct flight is the easiest way to get to your destination. The following airlines operate non-stop flights from Lisbon to Santiago:
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We keep tight track on airlines' pre-holidays sales and other special offers occurences all the time to let you save maximum amount of funds while traveling to your family or just going out on vacation.
The cheapest one-way flight from Lisbon to Santiago departs on 01/29/2026, is operated by Air Europa and costs $604
The cheapest roundtrip flight from Lisbon to Santiago departs on 02/07/2026, is operated by Air Canada and costs $839
Fastest flight from Lisbon to Santiago takes 23h 5m
There are no direct flights on this route.
The distance between Lisbon and Santiago is 10215km (6333 miles). The time difference between Lisbon and Santiago is 4h
Unable to find information about the schedule of direct flights from
Lisbon Humberto Delgado Airport (LIS) is Portugal’s main international gateway and typically functions as a full-service hub with a mix of legacy carriers and low-cost airlines. Located about 7 km northeast of the city centre, it can be reached in roughly 20–30 minutes by metro (around €1.50–€2.00), 20–40 minutes by taxi or ride-share (fares varying by time and traffic), and 25–45 minutes by airport shuttle or bus. The airport usually offers a broad choice of connections across Europe, Africa and the Americas, with generally mid-range fares compared with other Western European capitals. Pros: frequent transit links and extensive services; cons: can be busy during peak hours and traffic may affect road travel times.
Comodoro Arturo Merino Benítez (SCL) is Santiago’s main international gateway and typically functions as Chile’s busiest hub, serving full-service carriers like LATAM alongside a growing number of low-cost and regional airlines. Located about 15–20 km northwest of downtown, it’s usually reachable in 20–40 minutes by taxi or ride-hail (fares commonly varying with traffic), or by airport bus and shuttle services that can take 30–50 minutes at lower cost. Transfers to intercity buses and car rental desks are convenient for onward travel. Pros: comprehensive services, frequent international connections and modern terminals; cons: can be busy at peak times and delays to the city may occur with congestion.
There appear to be no non-stop flights from Lisbon to Santiago at this time.... Well, or something went wrong on our side and we couldn't find anything
starting at $604
starting at $617
The route Lisbon — Santiago is served by several airlines: Air Europa and LATAM Chile. This gives passengers more freedom in choosing flights. You can consider not only the price but also schedules, baggage policies, and onboard service. Our service compares all offers so you can find tickets from $604 and choose the most convenient option. Thanks to airline competition, you may also find promotional fares or special offers, helping you save even more. Plan your trip in advance and choose the best flights without overpaying.
The cheapest flight ticket from Lisbon to Santiago according to data for the last 48 hours costs $604
Often the best time to buy tickets from Lisbon to Santiago is 2 months before departure.
Based on statistics over the past years, the lowest prices for flights from Lisbon to Santiago can be found flying in these months: April, December.
The fastest flights from Lisbon to Santiago start from 23 hours 5 minutes in the air.
The following airlines operate direct flights on the route Lisbon — Santiago:
We couldn't find any special offers for flights from Lisbon to Santiago