There appear to be no non-stop flights from Jacksonville to Santiago at this time.... Well, or something went wrong on our side and we couldn't find anything
Compare fares and flight options for Jacksonville — Santiago. Prices can change; check availability when searching.
A non-stop flight is the most convenient and comfortable way to fly from Jacksonville to Santiago, despite the fact that sometimes flights with transfers can cost significantly less.
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There appear to be no non-stop flights from Jacksonville to Santiago at this time.... Well, or something went wrong on our side and we couldn't find anything
starting at $301
No direct offers were found for this route.
Flights on Jacksonville — Santiago: the offers found include JetBlue Airways tickets from $301. Compare options for your travel dates.
The cheapest one-way flight from Jacksonville to Santiago departs on 12/25/2026, is operated by JetBlue Airways and costs $301
The cheapest roundtrip flight from Jacksonville to Santiago departs on 12/25/2026, is operated by American Airlines and costs $768
Fastest flight from Jacksonville to Santiago takes 16h 49m
The straight-line distance between Jacksonville and Santiago is 1647km.
Direct-flight weekdays and the fastest option are based on the offers found.
The cheapest flight ticket from Jacksonville to Santiago according to data for the last 48 hours costs $301
The lowest prices in the available monthly data for Jacksonville — Santiago are in: December. Prices can change.
The shortest duration among the offers found for Jacksonville — Santiago is 16 hours 49 minutes, including connections if present.
We couldn't find any special offers for flights from Jacksonville to Santiago