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Fly from Detroit to San Francisco with confidence—our search scans over 700 airlines, 50+ travel agencies and 5+ top booking systems to uncover the best prices, schedules and ticket conditions for your trip. Compare nonstop and connecting options in seconds and lock in the flight that fits your budget and timetable.
A direct flight is the easiest way to get to your destination. The following airlines operate non-stop flights from Detroit to San Francisco:
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Fly nonstop from Detroit to San Francisco for the quickest, most convenient way to cross the country—less airport hassle and more time to enjoy your Bay Area plans. While connecting options can sometimes be cheaper, a direct flight saves hours and delivers a more comfortable, stress-free journey worth the small premium.
Detroit Metropolitan Wayne County Airport (DTW) is the region’s primary international hub, serving major network carriers like Delta alongside several domestic and international airlines; it typically handles the bulk of long-haul and connecting traffic. Located about 20 miles (≈32 km) southwest of downtown Detroit, travel to the city center usually takes 25–40 minutes by car depending on traffic. Ground options include rental cars and taxis, plus ride-hailing services; the SMART bus and the QLine/People Mover combination can be used with longer transfer times, and shuttle fares are generally modest while taxi/ride-hail costs can be mid-range for the distance. DTW is often seen as comfortable and efficient with extensive amenities and multiple terminals, though peak hours can mean busy security lines and longer walking distances between gates.
San Francisco International Airport (SFO) serves as the region’s main international gateway and a major West Coast hub, typically handling a mix of full-service carriers and several international airlines alongside some low-cost operators. Located about 13 miles south of downtown San Francisco, it’s usually reachable by BART in roughly 30–45 minutes (fare commonly in the low–mid single digits) or by taxi/rideshare in about 25–40 minutes depending on traffic (fares can vary significantly). Ground options also include airport shuttles and regional buses. Pros: extensive international connections and on-site amenities; cons: can be busy and security lines may be long during peak times.
Detroit — San Francisco
03/10/2026
Departure
Direct flight
UA331
starting at $422
Detroit — San Francisco
03/01/2026
Departure
Direct flight
UA2229
starting at $409
starting at $409
starting at $92
starting at $177
starting at $269
More than 4 airlines operate flights from Detroit to San Francisco, including United Airlines, Frontier Airlines, Spirit Airlines, and Alaska Airlines. This is a popular route, so passengers can choose tickets based on budget and preferences. Ticket prices start from $92, and our service lets you instantly compare all options. The variety of offers simplifies planning: you can choose budget fares or more comfortable options with baggage included or extra services. We help you find the best deals so your trip is cost-efficient.
The cheapest one-way flight from Detroit to San Francisco departs on 03/10/2026, is operated by Frontier Airlines and costs $92
The cheapest roundtrip flight from Detroit to San Francisco departs on 04/21/2026, is operated by Frontier Airlines and costs $210
Fastest flight from Detroit to San Francisco takes 8h 34m
There are direct flights on this route 2 days a week: Su and Tu
The distance between Detroit and San Francisco is 3358km (2082 miles). The time difference between Detroit and San Francisco is 3h
The cheapest flight ticket from Detroit to San Francisco according to data for the last 48 hours costs $92
Often the best time to buy tickets from Detroit to San Francisco is 2 months before departure.
Based on statistics over the past years, the lowest prices for flights from Detroit to San Francisco can be found flying in these months: March, February.
The fastest flights from Detroit to San Francisco start from 8 hours 34 minutes in the air.
The following airlines operate direct flights on the route Detroit — San Francisco: United Airlines
The cost of a one-way flight from Detroit to San Francisco ranges from $92 (March 2026) to $269 (February 2026). On average, the ticket price is about $181–$269.