ITA Airways
Su, Tu, Th, Fr, and Sa
starting at $818
Flaut.Travel was designed and developed by a team dedicated to making the process of searching, comparing and booking airline tickets as easy and convenient as possible. Our service helps travelers to find and buy the cheapest flights from Rome to San Francisco. We have connected more than 40 airlines and airline ticketing agencies to help you find the most suitable and affordable flight option.
A non-stop flight is the most convenient and comfortable way to fly from Rome to San Francisco, despite the fact that sometimes flights with transfers can cost significantly less.
The only airline operating direct flights from Rome to San Francisco is ITA Airways. Flights operate every day except Monday and Wednesday.
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Answers to questions about the route that travelers are most interested in.
We keep tight track on airlines' pre-holidays sales and other special offers occurences all the time to let you save maximum amount of funds while traveling to your family or just going out on vacation.
ITA Airways
Su, Tu, Th, Fr, and Sa
starting at $818
Rome — San Francisco
06/25/2026
Departure
Direct flight
UA506
starting at $1,537
Rome — San Francisco
08/01/2026
Departure
Direct flight
AZ640
starting at $1,245
Rome — San Francisco
08/03/2026
Departure
Direct flight
AZ640
starting at $1,122
starting at $1,537
starting at $1,122
starting at $792
starting at $815
The route Rome — San Francisco is served by many carriers — 4 in total, including United Airlines, ITA Airways, Aer Lingus, and LC Busre SAC. This gives passengers wide opportunities: from finding the lowest fare (from $792) to selecting flights by schedule or service class. Our service aggregates data from multiple booking systems so you can compare offers in one place. This saves time and money: no need to check dozens of sites — just pick the right option and book online.
The cheapest one-way flight from Rome to San Francisco departs on 08/03/2026, is operated by Aer Lingus and costs $792
The cheapest roundtrip flight from Rome to San Francisco departs on 09/01/2026, is operated by Condor and costs $625
Fastest flight from Rome to San Francisco takes 1d 0h 29m
There are direct flights on this route 3 days a week: Mo, Th, and Sa
The distance between Rome and San Francisco is 10047km (6229 miles). The time difference between Rome and San Francisco is 9h
The cheapest flight ticket from Rome to San Francisco according to data for the last 48 hours costs $792
Often the best time to buy tickets from Rome to San Francisco is 2 months before departure.
Based on statistics over the past years, the lowest prices for flights from Rome to San Francisco can be found flying in these months: May, January, August.
The fastest flights from Rome to San Francisco start from 29 minutes in the air.
The following airlines operate direct flights on the route Rome — San Francisco: United Airlines, ITA Airways
In different months, ticket prices from Rome to San Francisco vary: minimum — $442 (May 2026), maximum — $597 (August 2026). Typically, the flight costs $541–$1,182.
Tickets from Rome to San Francisco are getting more expensive each month. From May 2026 to January 2027, the increase reached 33%, with prices now at $586. It's unlikely to get cheaper than the current level.
The most significant price increase was from May 2026 to January 2027 — up 33%. The best time to fly is May 2026–August 2026, when the average price is $519. In August 2026–January 2027, tickets cost around $591.
Given the rising prices, it's best not to delay your purchase. Flying in May 2026–August 2026 can save you up to 12% compared to the most expensive months.
Price variation across months on this route is 13.1%. Your choice of departure month significantly affects the total flight cost.
We couldn't find any special offers for flights from Rome to San Francisco
