starting at $898
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starting at $548
Compare airlines, prices, and flight durations for your trip
Flaut.Travel was designed and developed by a team dedicated to making the process of searching, comparing and booking airline tickets as easy and convenient as possible. Our service helps travelers to find and buy the cheapest flights from Rome to San Francisco. We have connected more than 40 airlines and airline ticketing agencies to help you find the most suitable and affordable flight option.
In different months, ticket prices from Rome to San Francisco vary: minimum — $387 (April 2026), maximum — $592 (February 2026). Typically, the flight costs $490–$1,052.
A non-stop flight is the most convenient and comfortable way to fly from Rome to San Francisco, despite the fact that sometimes flights with transfers can cost significantly less.
A direct flight is the easiest way to get to your destination. The following airlines operate non-stop flights from Rome to San Francisco:
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Answers to questions about the route that travelers are most interested in.
We keep tight track on airlines' pre-holidays sales and other special offers occurences all the time to let you save maximum amount of funds while traveling to your family or just going out on vacation.
The route Rome — San Francisco is served by many carriers — 11 in total, including ITA Airways, United Airlines, Westjet, Ryanair, LC Busre SAC, TAP Portugal, Finnair, Vueling, American Airlines, British Airways, and Turkish Airlines. This gives passengers wide opportunities: from finding the lowest fare (from $378) to selecting flights by schedule or service class. Our service aggregates data from multiple booking systems so you can compare offers in one place. This saves time and money: no need to check dozens of sites — just pick the right option and book online.
starting at $898
starting at $1,414
starting at $378
starting at $396
starting at $405
starting at $453
starting at $455
starting at $493
starting at $502
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starting at $548
Rome — San Francisco
03/02/2026
Departure
Direct flight
AZ640
starting at $905
Rome — San Francisco
03/21/2026
Departure
Direct flight
AZ640
starting at $1,025
Rome — San Francisco
03/31/2026
Departure
Direct flight
AZ640
starting at $999
Rome — San Francisco
04/04/2026
Departure
Direct flight
UA506
starting at $1,414
Rome — San Francisco
04/05/2026
Departure
Direct flight
UA506
starting at $1,870
Rome — San Francisco
06/19/2026
Departure
Direct flight
UA506
starting at $1,948
Rome — San Francisco
09/17/2026
Departure
Direct flight
AZ640
starting at $1,025
Rome — San Francisco
09/19/2026
Departure
Direct flight
UA506
starting at $2,048
Rome — San Francisco
09/20/2026
Departure
Direct flight
AZ640
starting at $981
Rome — San Francisco
09/21/2026
Departure
Direct flight
AZ640
starting at $898
Unable to find information about the schedule of direct flights from
The cheapest flight ticket from Rome to San Francisco according to data for the last 48 hours costs $378
Often the best time to buy tickets from Rome to San Francisco is 2 months before departure.
Based on statistics over the past years, the lowest prices for flights from Rome to San Francisco can be found flying in these months: April, March, June.
The fastest flights from Rome to San Francisco start from 3 hours 30 minutes in the air.
The following airlines operate direct flights on the route Rome — San Francisco: ITA Airways, United Airlines
The cheapest one-way flight from Rome to San Francisco departs on 04/04/2026, is operated by Westjet and costs $378
The cheapest roundtrip flight from Rome to San Francisco departs on 05/17/2026, is operated by ITA Airways and costs $609
Fastest flight from Rome to San Francisco takes 1d 3h 30m
There are direct flights on this route 7 days a week: Su, Mo, Tu, We, Th, Fr, and Sa
The distance between Rome and San Francisco is 10047km (6229 miles). The average flight duration is 19h 5m. The time difference between Rome and San Francisco is 9h
We couldn't find any special offers for flights from Rome to San Francisco