Cheap Flights from Rome to San Francisco — $379

The route Rome — San Francisco is served by many carriers — 11 in total, including ITA Airways, United Airlines, Westjet, Ryanair, LC Busre SAC, TAP Portugal, Finnair, Vueling, American Airlines, British Airways, and Turkish Airlines. This gives passengers wide opportunities: from finding the lowest fare (from $379) to selecting flights by schedule or service class. Our service aggregates data from multiple booking systems so you can compare offers in one place. This saves time and money: no need to check dozens of sites — just pick the right option and book online.

A non-stop flight is the most convenient and comfortable way to fly from Rome to San Francisco, despite the fact that sometimes flights with transfers can cost significantly less.