There are most likely no direct flights on the Quito — Santa Cruz route
Flaut.Travel was designed and developed by a team dedicated to making the process of searching, comparing and booking airline tickets as easy and convenient as possible. Our service helps travelers to find and buy the cheapest flights from Quito to Santa Cruz. We have connected more than 40 airlines and airline ticketing agencies to help you find the most suitable and affordable flight option.
The cost of a one-way flight from Quito to Santa Cruz ranges from $353 (August 2026) to $377 (December 2026). On average, the ticket price is about $365–$743.
A non-stop flight is the most convenient and comfortable way to fly from Quito to Santa Cruz, despite the fact that sometimes flights with transfers can cost significantly less.
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Answers to questions about the route that travelers are most interested in.
We keep tight track on airlines' pre-holidays sales and other special offers occurences all the time to let you save maximum amount of funds while traveling to your family or just going out on vacation.
Flight prices from Quito to Santa Cruz barely change from month to month. You can comfortably choose any convenient dates — there won't be a significant overpayment.
There is a slight difference: it's a bit cheaper in August 2026–September 2026 (averaging $360) and slightly more in September 2026–December 2026 ($371). But overall, the difference is small.
On this route, you don't need to target specific months — prices are stable. The difference between the cheapest and most expensive period is only 3%. Book whenever it's convenient.
Monthly price variation is just 2.7%. Ticket costs on this route are among the most predictable.
There are most likely no direct flights on the Quito — Santa Cruz route
There appear to be no non-stop flights from Quito to Santa Cruz at this time.... Well, or something went wrong on our side and we couldn't find anything
starting at $368
starting at $387
starting at $393
starting at $401
More than 4 airlines operate flights from Quito to Santa Cruz, including Copa Airlines, B&H Airlines, Avianca, and Avianca Ecuador. This is a popular route, so passengers can choose tickets based on budget and preferences. Ticket prices start from $368, and our service lets you instantly compare all options. The variety of offers simplifies planning: you can choose budget fares or more comfortable options with baggage included or extra services. We help you find the best deals so your trip is cost-efficient.
The cheapest flight ticket from Quito to Santa Cruz according to data for the last 48 hours costs $368
Often the best time to buy tickets from Quito to Santa Cruz is 2 months before departure.
Based on statistics over the past years, the lowest prices for flights from Quito to Santa Cruz can be found flying in these months: August, September, December.
The fastest flights from Quito to Santa Cruz start from 6 hours 40 minutes in the air.
The following airlines operate direct flights on the route Quito — Santa Cruz:
We couldn't find any special offers for flights from Quito to Santa Cruz
The cheapest one-way flight from Quito to Santa Cruz departs on 09/25/2026, is operated by Copa Airlines and costs $368
The cheapest roundtrip flight from Quito to Santa Cruz departs on 09/25/2026, is operated by Avianca and costs $727
Fastest flight from Quito to Santa Cruz takes 6h 40m
There are no direct flights on this route.
The distance between Quito and Santa Cruz is 2578km (1598 miles). The time difference between Quito and Santa Cruz is 1h
