Schedule of direct flights from Panama City to Santiago
A direct flight is the easiest way to get to your destination. The following airlines operate non-stop flights from Panama City to Santiago:
Panama City airports overview
Santiago airports overview
Frequently asked questions (FAQ)
Answers to questions about the route that travelers are most interested in.
Special offers and sales on air tickets from Panama City to Santiago
We keep tight track on airlines' pre-holidays sales and other special offers occurences all the time to let you save maximum amount of funds while traveling to your family or just going out on vacation.
Alternative routes
•••••••••••••••••••
Cheapest one way flight
$266
Avianca
1 transfer
14h 20m
05/07/2025
The cheapest one-way flight from Panama City to Santiago departs on 05/07/2025, is operated by Avianca and costs $266
Cheapest round trip flight
$467
Avianca
1 transfer
1d 1h
05/05/2025
The cheapest roundtrip flight from Panama City to Santiago departs on 05/05/2025, is operated by Avianca and costs $467
The fastest flight
9 hours
Fastest flight from Panama City to Santiago takes 9 hours
Direct flights
No direct flights
There are no direct flights on this route.
Earliest flight
11:47 AM
Latest flight
9:30 PM
Direct flights count
44
Distance
4810km
Timezone difference
1h
The distance between Panama City and Santiago is 4810km (2982 miles).There are 44 direct flights from Panama City to Santiago.The time difference between Panama City and Santiago is 1h .Flights from Panama City begin at 11:47 AM.The latest flight from Panama City departs at 9:30 PM.
Below you will find a list of airlines operating flights on the Panama City — Santiago route and the starting prices for flights of each specific airline on it.
We carefully collect statistics on the search and pricing of airlines and, based on these data, we make an assumption about future prices. Thus, you can better understand which season is the cheapest to fly from Panama City to Santiago
May 2025
Lowest price
on average:
$329
March 2025
Highest price
on average:
$390
Flaut.Travel was designed and developed by a team dedicated to making the process of searching, comparing and booking airline tickets as easy and convenient as possible. Our service helps travelers to find and buy the cheapest flights from Panama City to Santiago. We have connected more than 40 airlines and airline ticketing agencies to help you find the most suitable and affordable flight option.
A direct flight is the most convenient and comfortable way to fly from Panama City to Santiago, despite the fact that sometimes flights with transfers can cost significantly less.
Unable to find information about the schedule of direct flights from
Unfortunately, we were unable to find any airports in Santiago. We'll try to look better another time
Unfortunately, we were unable to find any airports in Panama City. We'll try to look better another time
We couldn't find any special offers for flights from Panama City to Santiago
There appear to be no direct flights from Panama City to Santiago at this time.... Well, or something went wrong on our side and we couldn't find anything
How much is the cheapest flight ticket from Panama City to Santiago?
The cheapest flight ticket from Panama City to Santiago according to data for the last 48 hours costs $266
When is the best time to buy air tickets on the route Panama City — Santiago?
Often the best time to buy tickets from Panama City to Santiago is 2 months before departure.
When is the cheapest time of year to fly from Panama City to Santiago?
Based on statistics over the past years, the lowest prices for flights from Panama City to Santiago can be found flying in these months: May, March.
How long does it take to fly from Panama City to Santiago?
The fastest flights from Panama City to Santiago start from 9 hours in the air.
Which airline can fly direct from Panama City to Santiago?
The following airlines operate direct flights on the route Panama City — Santiago:
