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A non-stop flight is the most convenient and comfortable way to fly from Panama City to Grand Cayman Island, despite the fact that sometimes flights with transfers can cost significantly less.
A direct flight is the easiest way to get to your destination. The following airlines operate non-stop flights from Panama City to Grand Cayman Island:
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Answers to questions about the route that travelers are most interested in.
We keep tight track on airlines' pre-holidays sales and other special offers occurences all the time to let you save maximum amount of funds while traveling to your family or just going out on vacation.
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We carefully collect statistics on the search and pricing of airlines and, based on these data, we make an assumption about future prices. Thus, you can better understand which season is the cheapest to fly from Panama City to Grand Cayman Island
Flaut.Travel was designed and developed by a team dedicated to making the process of searching, comparing and booking airline tickets as easy and convenient as possible. Our service helps travelers to find and buy the cheapest flights from Panama City to Grand Cayman Island. We have connected more than 40 airlines and airline ticketing agencies to help you find the most suitable and affordable flight option.
Panama City — Grand Cayman Island
09/17/2026
Departure
Direct flight
KX853
starting at $392
The Panama City — Grand Cayman Island route is served by multiple airlines, including Cayman Airways, Copa Airlines, and Avianca. This is convenient for those who want the best balance of price, schedule, and travel conditions. Tickets start from $288, and depending on season and promotions, even better deals may appear. With our service, you can easily compare available options and book tickets that match your plans. The variety of carriers allows flexible choices and comfortable travel without overpaying.
The cheapest flight ticket from Panama City to Grand Cayman Island according to data for the last 48 hours costs $288
Often the best time to buy tickets from Panama City to Grand Cayman Island is 2 months before departure.
Based on statistics over the past years, the lowest prices for flights from Panama City to Grand Cayman Island can be found flying in these months: February.
The fastest flights from Panama City to Grand Cayman Island start from 14 hours 2 minutes in the air.
The following airlines operate direct flights on the route Panama City — Grand Cayman Island: Cayman Airways
The cheapest one-way flight from Panama City to Grand Cayman Island departs on 09/18/2026, is operated by Copa Airlines and costs $288
There is no information about the cheapest roundtrip flight from Panama City to Grand Cayman Island
Fastest flight from Panama City to Grand Cayman Island takes 14h 2m
There are direct flights on this route 1 day a week: Th
The distance between Panama City and Grand Cayman Island is 1162km (720 miles). There are 1 direct flight from Panama City to Grand Cayman Island. Panama City and Grand Cayman Island are in the same time zone. Flights from Panama City begin at 3:00 PM. The latest flight from Panama City departs at 3:00 PM
We couldn't find any special offers for flights from Panama City to Grand Cayman Island
