Unable to find information about the schedule of direct flights from
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Flaut.Travel was designed and developed by a team dedicated to making the process of searching, comparing and booking airline tickets as easy and convenient as possible. Our service helps travelers to find and buy the cheapest flights from Chicago to Panama City. We have connected more than 40 airlines and airline ticketing agencies to help you find the most suitable and affordable flight option.
A non-stop flight is the most convenient and comfortable way to fly from Chicago to Panama City, despite the fact that sometimes flights with transfers can cost significantly less.
A direct flight is the easiest way to get to your destination. The following airlines operate non-stop flights from Chicago to Panama City:
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Answers to questions about the route that travelers are most interested in.
We keep tight track on airlines' pre-holidays sales and other special offers occurences all the time to let you save maximum amount of funds while traveling to your family or just going out on vacation.
Unable to find information about the schedule of direct flights from
Chicago — Panama City
03/13/2026
Departure
Direct flight
WN4306
starting at $258
Chicago — Panama City
05/04/2026
Departure
Direct flight
UA1491
starting at $106
starting at $258
starting at $106
Flights from Chicago to Panama City are operated by several airlines — Southwest Airlines and United Airlines. This allows passengers to flexibly choose flights based on departure time, cost, and additional services. The minimum ticket price starts at $106, making this destination accessible to travelers with different budgets. We help compare all available options in real time, so you can book tickets at the best value for money. The service ensures transparent search and lets you book affordable flights in just a few clicks.
The cheapest flight ticket from Chicago to Panama City according to data for the last 48 hours costs $106
Often the best time to buy tickets from Chicago to Panama City is 2 months before departure.
Based on statistics over the past years, the lowest prices for flights from Chicago to Panama City can be found flying in these months: May, March.
The fastest flights from Chicago to Panama City start from 2 hours 31 minutes in the air.
The following airlines operate direct flights on the route Chicago — Panama City: Southwest Airlines, United Airlines
The cost of a one-way flight from Chicago to Panama City ranges from $106 (May 2026) to $157 (March 2026). On average, the ticket price is about $132–$157.
We couldn't find any special offers for flights from Chicago to Panama City
The cheapest one-way flight from Chicago to Panama City departs on 05/04/2026, is operated by United Airlines and costs $106
The cheapest roundtrip flight from Chicago to Panama City departs on 03/29/2026, is operated by United Airlines and costs $393
Fastest flight from Chicago to Panama City takes 2h 31m
There are direct flights on this route 2 days a week: Mo and Fr
The distance between Chicago and Panama City is 1314km (815 miles). Chicago and Panama City are in the same time zone