Cheap Flights from Cartagena to Santiago — $319

Flaut.Travel was designed and developed by a team dedicated to making the process of searching, comparing and booking airline tickets as easy and convenient as possible. Our service helps travelers to find and buy the cheapest flights from Cartagena to Santiago. We have connected more than 40 airlines and airline ticketing agencies to help you find the most suitable and affordable flight option.

A non-stop flight is the most convenient and comfortable way to fly from Cartagena to Santiago, despite the fact that sometimes flights with transfers can cost significantly less.

On the Cartagena — Santiago route, flights are operated only by Avianca. This simplifies the choice for passengers, as all tickets come from a single trusted carrier. Our service lets you instantly check fares for upcoming dates and find the most advantageous option. The minimum ticket price starts at $319, making this trip affordable for a wide range of travelers. To save even more, we recommend booking early and keeping an eye on promotions — Avianca regularly offers special deals.

The cost of a one-way flight from Cartagena to Santiago ranges from $199 (December 2025) to $337 (January 2026). On average, the ticket price is about $263–$590.