Cheap Flights from Cartagena to Panama City — $220

Find the best deals from Cartagena to Panama City in seconds — our search scans more than 700 airlines, over 50 agencies and 5+ top booking systems to uncover the cheapest fares, ideal schedules and flexible conditions for your trip. Whether you need a quick connection or a specific departure time, we compare options side-by-side so you can book confidently and save.

Rafael Núñez International Airport (CTG) serves Cartagena as the main international gateway and a convenient regional hub, handling a mix of legacy carriers, low-cost airlines and seasonal charters. It’s located about 6–10 km north of the historic center, with typical transfer times of 15–30 minutes by taxi or rideshare and 30–50 minutes by public bus; fares for taxis and rideshares can vary but are usually moderate, while buses are the cheapest option. The terminal is compact and generally easy to navigate, making arrivals and departures straightforward, though peak-season crowds and occasional delays can affect comfort. Travelers benefit from quick access to the walled city, but those seeking the lowest fares or late-night services may find fewer budget options than at larger Colombian hubs.

The cost of a one-way flight from Cartagena to Panama City ranges from $204 (April 2026) to $261 (June 2026). On average, the ticket price is about $240–$517.

Fly direct from Cartagena to Panama City for the quickest, most convenient trip between these vibrant Caribbean and Central American hubs — perfect when time matters and comfort counts. While you may occasionally find cheaper connecting options, a nonstop flight saves hours and hassles, letting you start exploring Panama City sooner.

Flights from Cartagena to Panama City are operated by several airlines — Copa Airlines, Avianca, and Aerorepublica. This allows passengers to flexibly choose flights based on departure time, cost, and additional services. The minimum ticket price starts at $220, making this destination accessible to travelers with different budgets. We help compare all available options in real time, so you can book tickets at the best value for money. The service ensures transparent search and lets you book affordable flights in just a few clicks.

Tocumen International (PTY) is Panama City’s main international gateway and a regional hub for connecting flights across the Americas, typically serving full-service carriers and a growing number of low-cost airlines. It sits about 24 km (15 miles) east of downtown Panama City, with road transfers taking roughly 30–45 minutes by taxi or ride-share depending on traffic; fares can typically range from about $25 to $40. Airport express buses and private shuttles are also common options and may be cheaper. Pros: good international connections, modern facilities and a wide range of services. Cons: can be busy and transfers sometimes require ample connection time due to size and peak-hour congestion.