Cheap Flights from Cartagena to Panama City Starting at $172
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Cheapest flights from Cartagena to Panama City
Find the best deals from Cartagena to Panama City in seconds — our search scans more than 700 airlines, over 50 agencies and 5+ top booking systems to uncover the cheapest fares, ideal schedules and flexible conditions for your trip. Whether you need a quick connection or a specific departure time, we compare options side-by-side so you can book confidently and save.
Remember that on average the ideal time to book flights is 2 months before departure!
Fly direct from Cartagena to Panama City for the quickest, most convenient trip between these vibrant Caribbean and Central American hubs — perfect when time matters and comfort counts. While you may occasionally find cheaper connecting options, a nonstop flight saves hours and hassles, letting you start exploring Panama City sooner.
Schedule of direct flights from Cartagena to Panama City
A direct flight is the easiest way to get to your destination. The following airlines operate non-stop flights from Cartagena to Panama City:
Cartagena airports overview
Panama City airports overview
Frequently asked questions (FAQ)
Answers to questions about the route that travelers are most interested in.
Special offers and sales on air tickets from Cartagena to Panama City
We keep tight track on airlines' pre-holidays sales and other special offers occurences all the time to let you save maximum amount of funds while traveling to your family or just going out on vacation.
Alternative routes
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Cheapest one way flight
$172
Avianca
1 transfer
6h 45m
12/15/2025
The cheapest one-way flight from Cartagena to Panama City departs on 12/15/2025, is operated by Avianca and costs $172
Cheapest round trip flight
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There is no information about the cheapest roundtrip flight from Cartagena to Panama City
The fastest flight
5h 35m
Fastest flight from Cartagena to Panama City takes 5h 35m
Direct flights
No direct flights
There are no direct flights on this route.
Earliest flight
6:20 AM
Latest flight
3:30 PM
Average flight duration
1h 18m
Direct flights count
34
Distance
467km
Timezone difference
0h
The distance between Cartagena and Panama City is 467km (290 miles). The average flight duration is 1h 18m. There are 34 direct flights from Cartagena to Panama City. Cartagena and Panama City are in the same time zone. Flights from Cartagena begin at 6:20 AM. The latest flight from Cartagena departs at 3:30 PM
December 2025
Lowest price
on average:
$170
January 2026
Highest price
on average:
$198
Avg Price
Flights from Cartagena to Panama City are operated by several airlines — Copa Airlines and Avianca. This allows passengers to flexibly choose flights based on departure time, cost, and additional services. The minimum ticket price starts at $172, making this destination accessible to travelers with different budgets. We help compare all available options in real time, so you can book tickets at the best value for money. The service ensures transparent search and lets you book affordable flights in just a few clicks.
Rafael Núñez International Airport (CTG) serves Cartagena as the main international gateway and a convenient regional hub, handling a mix of legacy carriers, low-cost airlines and seasonal charters. It’s located about 6–10 km north of the historic center, with typical transfer times of 15–30 minutes by taxi or rideshare and 30–50 minutes by public bus; fares for taxis and rideshares can vary but are usually moderate, while buses are the cheapest option. The terminal is compact and generally easy to navigate, making arrivals and departures straightforward, though peak-season crowds and occasional delays can affect comfort. Travelers benefit from quick access to the walled city, but those seeking the lowest fares or late-night services may find fewer budget options than at larger Colombian hubs.
Tocumen International (PTY) is Panama City’s main international gateway and a regional hub for connecting flights across the Americas, typically serving full-service carriers and a growing number of low-cost airlines. It sits about 24 km (15 miles) east of downtown Panama City, with road transfers taking roughly 30–45 minutes by taxi or ride-share depending on traffic; fares can typically range from about $25 to $40. Airport express buses and private shuttles are also common options and may be cheaper. Pros: good international connections, modern facilities and a wide range of services. Cons: can be busy and transfers sometimes require ample connection time due to size and peak-hour congestion.
We couldn't find any special offers for flights from Cartagena to Panama City
How much is the cheapest flight ticket from Cartagena to Panama City?
The cheapest flight ticket from Cartagena to Panama City according to data for the last 48 hours costs $172
When is the best time to buy air tickets on the route Cartagena — Panama City?
Often the best time to buy tickets from Cartagena to Panama City is 2 months before departure.
When is the cheapest time of year to fly from Cartagena to Panama City?
Based on statistics over the past years, the lowest prices for flights from Cartagena to Panama City can be found flying in these months: December, October, November.
How long does it take to fly from Cartagena to Panama City?
The fastest flights from Cartagena to Panama City start from 5 hours 35 minutes in the air.
Which airline can fly direct from Cartagena to Panama City?
The following airlines operate direct flights on the route Cartagena — Panama City: Copa Airlines
The cost of a one-way flight from Cartagena to Panama City ranges from $170 (December 2025) to $198 (January 2026). On average, the ticket price is about $176–$180.
