Cheap Flights from Cartagena to Panama City Starting at $173
Helping travelers to find the best flight offers
Cheapest flights from Cartagena to Panama City
Find the best deals from Cartagena to Panama City in seconds — our search scans more than 700 airlines, over 50 agencies and 5+ top booking systems to uncover the cheapest fares, ideal schedules and flexible conditions for your trip. Whether you need a quick connection or a specific departure time, we compare options side-by-side so you can book confidently and save.
Remember that on average the ideal time to book flights is 2 months before departure!
Fly direct from Cartagena to Panama City for the quickest, most convenient trip between these vibrant Caribbean and Central American hubs — perfect when time matters and comfort counts. While you may occasionally find cheaper connecting options, a nonstop flight saves hours and hassles, letting you start exploring Panama City sooner.
Schedule of direct flights from Cartagena to Panama City
A direct flight is the easiest way to get to your destination. The following airlines operate non-stop flights from Cartagena to Panama City:
Cartagena airports overview
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Panama City airports overview
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Frequently asked questions (FAQ)
Answers to questions about the route that travelers are most interested in.
Special offers and sales on air tickets from Cartagena to Panama City
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Alternative routes
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Cheapest one way flight
$173
Avianca
1 transfer
10h 55m
01/20/2026
The cheapest one-way flight from Cartagena to Panama City departs on 01/20/2026, is operated by Avianca and costs $173
Cheapest round trip flight
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There is no information about the cheapest roundtrip flight from Cartagena to Panama City
The fastest flight
1h 22m
Fastest flight from Cartagena to Panama City takes 1h 22m
Direct flights
Once a week
There are direct flights on this route 1 day a week: Th
Earliest flight
6:20 AM
Latest flight
3:30 PM
Average flight duration
1h 18m
Direct flights count
34
Distance
467km
Timezone difference
0h
The distance between Cartagena and Panama City is 467km (290 miles). The average flight duration is 1h 18m. There are 34 direct flights from Cartagena to Panama City. Cartagena and Panama City are in the same time zone. Flights from Cartagena begin at 6:20 AM. The latest flight from Cartagena departs at 3:30 PM
January 2026
Lowest price
on average:
$173
February 2026
Highest price
on average:
$195
Avg Price
More than 4 airlines operate flights from Cartagena to Panama City, including Copa Airlines, Avianca, B&H Airlines, and LATAM Chile. This is a popular route, so passengers can choose tickets based on budget and preferences. Ticket prices start from $173, and our service lets you instantly compare all options. The variety of offers simplifies planning: you can choose budget fares or more comfortable options with baggage included or extra services. We help you find the best deals so your trip is cost-efficient.
Rafael Núñez International Airport (CTG) serves Cartagena as the main international gateway and a convenient regional hub, handling a mix of legacy carriers, low-cost airlines and seasonal charters. It’s located about 6–10 km north of the historic center, with typical transfer times of 15–30 minutes by taxi or rideshare and 30–50 minutes by public bus; fares for taxis and rideshares can vary but are usually moderate, while buses are the cheapest option. The terminal is compact and generally easy to navigate, making arrivals and departures straightforward, though peak-season crowds and occasional delays can affect comfort. Travelers benefit from quick access to the walled city, but those seeking the lowest fares or late-night services may find fewer budget options than at larger Colombian hubs.
Tocumen International (PTY) is Panama City’s main international gateway and a regional hub for connecting flights across the Americas, typically serving full-service carriers and a growing number of low-cost airlines. It sits about 24 km (15 miles) east of downtown Panama City, with road transfers taking roughly 30–45 minutes by taxi or ride-share depending on traffic; fares can typically range from about $25 to $40. Airport express buses and private shuttles are also common options and may be cheaper. Pros: good international connections, modern facilities and a wide range of services. Cons: can be busy and transfers sometimes require ample connection time due to size and peak-hour congestion.
We couldn't find any special offers for flights from Cartagena to Panama City
How much is the cheapest flight ticket from Cartagena to Panama City?
The cheapest flight ticket from Cartagena to Panama City according to data for the last 48 hours costs $173
When is the best time to buy air tickets on the route Cartagena — Panama City?
Often the best time to buy tickets from Cartagena to Panama City is 2 months before departure.
When is the cheapest time of year to fly from Cartagena to Panama City?
Based on statistics over the past years, the lowest prices for flights from Cartagena to Panama City can be found flying in these months: January, December, February.
How long does it take to fly from Cartagena to Panama City?
The fastest flights from Cartagena to Panama City start from 1 hour 22 minutes in the air.
Which airline can fly direct from Cartagena to Panama City?
The following airlines operate direct flights on the route Cartagena — Panama City: Copa Airlines
The cost of a one-way flight from Cartagena to Panama City ranges from $173 (January 2026) to $195 (February 2026). On average, the ticket price is about $183–$376.
