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Flying from Cape Town to Santiago? Our search scans over 700 airlines, 50+ agencies and more than 5 top booking systems to uncover the best fares, flight times and flexible booking conditions for your long-haul trip. Compare options in seconds and book the itinerary that fits your budget and schedule with confidence.
A direct flight is the easiest way to get to your destination. The following airlines operate non-stop flights from Cape Town to Santiago:
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Cape Town International is the city’s primary international gateway and typically functions as a full-service hub for major carriers alongside a range of low-cost airlines. Located about 20–25 km from the city centre, transfers commonly take 20–40 minutes by MyCiTi bus or 20–45 minutes by taxi/rideshare, with fares varying by service and traffic; airport shuttles and car hires are also widely available. The airport usually offers a broad mix of long-haul and regional connections, making it convenient for international travelers, while budget flyers can often find competitive domestic links. Pros: modern facilities and frequent services; cons: transfer times can swell in peak traffic and some fares can be higher than secondary airports.
Fly nonstop from Cape Town to Santiago for the quickest, most convenient way to bridge South Africa and Chile — less time in transit and more time enjoying your destination. While connecting options can sometimes come with lower fares, direct flights minimize layovers and hassle, making them the smarter choice when comfort and speed matter. Book now to secure a smooth, time-saving journey across continents.
There appear to be no non-stop flights from Cape Town to Santiago at this time.... Well, or something went wrong on our side and we couldn't find anything
starting at $541
starting at $732
starting at $1,123
starting at $1,347
More than 4 airlines operate flights from Cape Town to Santiago, including TAAG Angola Airlines, Airlink, Transasia Airways, and Qatar Airways. This is a popular route, so passengers can choose tickets based on budget and preferences. Ticket prices start from $541, and our service lets you instantly compare all options. The variety of offers simplifies planning: you can choose budget fares or more comfortable options with baggage included or extra services. We help you find the best deals so your trip is cost-efficient.
The cheapest one-way flight from Cape Town to Santiago departs on 03/15/2026, is operated by TAAG Angola Airlines and costs $541
There is no information about the cheapest roundtrip flight from Cape Town to Santiago
Fastest flight from Cape Town to Santiago takes 21h 50m
There are no direct flights on this route.
The distance between Cape Town and Santiago is 7945km (4926 miles). The time difference between Cape Town and Santiago is 6h
Santiago’s main gateway is Comodoro Arturo Merino Benítez International (SCL), the country’s primary international hub handling most long-haul and regional flights and hosting full-service carriers alongside several low-cost operators. It sits about 15–20 km northwest of downtown Santiago; road transfers typically take 20–40 minutes depending on traffic, with airport buses and shared shuttles often costing modest fares while taxis and ride-hailing trips can be faster but pricier. A smaller military/aviation field exists for limited domestic or charter operations, but SCL covers nearly all passenger needs. Pros: modern facilities and many route options; cons: peak-hour congestion and occasional delays when traffic to the city is heavy.
The cheapest flight ticket from Cape Town to Santiago according to data for the last 48 hours costs $541
Often the best time to buy tickets from Cape Town to Santiago is 2 months before departure.
Based on statistics over the past years, the lowest prices for flights from Cape Town to Santiago can be found flying in these months: March, April, February.
The fastest flights from Cape Town to Santiago start from 21 hours 50 minutes in the air.
The following airlines operate direct flights on the route Cape Town — Santiago:
The cost of a one-way flight from Cape Town to Santiago ranges from $614 (March 2026) to $875 (February 2026). On average, the ticket price is about $714–$1,528.
We couldn't find any special offers for flights from Cape Town to Santiago